Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11909983 | 0.86 | PTGDR2 (0.41) | PTGDR2NOD2NOD1PPARGPPARD | |
| SCHEMBL10313796 | 0.84 | NOD2 (0.42) | PTGDR2NOD2NOD1PPARGPPARD | |
| SCHEMBL12908057 | 0.82 | ALOX5 (0.41) | PTGDR2NOD2NOD1PPARGPPARD | |
| SCHEMBL12908806 | 0.78 | NOD2 (0.51) | PTGDR2NOD2NOD1PPARGPPARD | |
| SCHEMBL10003441 | 0.74 | ALOX5 (0.37) | PTGDR2NOD2NOD1PPARGPPARD | |
| SCHEMBL10003439 | 0.74 | ALOX5 (0.37) | PTGDR2NOD2NOD1PPARGPPARD | |
| SCHEMBL12908808 | 0.73 | PPARG (0.48) | PTGDR2NOD2NOD1PPARGPPARD | |
| SCHEMBL10003682 | 0.73 | NOD2 (0.44) | PTGDR2NOD2NOD1PPARGPPARD | |
| SCHEMBL10313746 | 0.71 | NOD1 (0.45) | PTGDR2NOD2NOD1PPARGPPARD | |
| SCHEMBL12908515 | 0.71 | NOD1 (0.50) | PTGDR2NOD2NOD1PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2471786-A1 | AMINOPYRAZOLE DERIVATIVE | Chugai Seiyaku Kabushiki Kaisha (JP) | 2012-07-04 | — | — | EP | disclosed |