Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 5/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | CPS1 | P31327 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GPR183 | P32249 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LSS | P48449 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1031081 | 0.83 | ALDH1A1 (0.48) | TP53GPR183ALDH1A1LMNAGAA | |
| SCHEMBL1029933 | 0.78 | ALDH1A1 (0.58) | ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL1029484 | 0.76 | HSD11B1 (0.47) | L3MBTL1ALDH1A1 | |
| SCHEMBL1031438 | 0.75 | TP53 (0.46) | DRD3TP53HTTALDH1A1LMNA | |
| SCHEMBL1031811 | 0.74 | HPGD (0.54) | TP53HTTALDH1A1LMNAKDM4E | |
| SCHEMBL1028175 | 0.73 | TP53 (0.52) | TP53HTTALDH1A1LMNAMEN1 | |
| SCHEMBL1030249 | 0.72 | ALDH1A1 (0.46) | HTTL3MBTL1GPR183ALDH1A1LMNA | |
| SCHEMBL19284240 | 0.72 | GHSR (0.64) | GHSRDRD3DRD2CPS1HTT | |
| SCHEMBL1032620 | 0.72 | HTT (0.53) | TP53HTTALDH1A1LMNAMEN1 | |
| SCHEMBL26828138 | 0.72 | DRD3 (0.61) | GHSRDRD3DRD2CPS1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035375-B1 | 1,3-DISUBSTITUTED 4-METHYL-1H-PYRROLE-2-CARBOXAMIDES AND THEIR USE FOR THE MANUFACTURE OF MEDICAMENTS | GRUENENTHAL GMBH (DE) | 2011-01-19 | — | — | EP | claimed |