Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1030828 | 0.91 | MAPT (0.47) | ALDH1A1THRBRXFP1 | |
| SCHEMBL1031510 | 0.88 | MEN1 (0.51) | — | |
| SCHEMBL1029485 | 0.86 | HSD11B1 (0.46) | HSD11B1ALDH1A1PKMCA12CA1 | |
| SCHEMBL1034078 | 0.86 | MAPT (0.46) | ALDH1A1 | |
| SCHEMBL1031811 | 0.84 | HPGD (0.54) | ALDH1A1PKM | |
| SCHEMBL1028175 | 0.83 | TP53 (0.52) | ALDH1A1PKM | |
| SCHEMBL1030438 | 0.82 | MEN1 (0.61) | ALDH1A1PKMTHRBL3MBTL1 | |
| SCHEMBL1032620 | 0.82 | HTT (0.53) | ALDH1A1 | |
| SCHEMBL1031573 | 0.82 | KMT2A (0.52) | HSD11B1ALDH1A1 | |
| SCHEMBL1032634 | 0.80 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035375-B1 | 1,3-DISUBSTITUTED 4-METHYL-1H-PYRROLE-2-CARBOXAMIDES AND THEIR USE FOR THE MANUFACTURE OF MEDICAMENTS | GRUENENTHAL GMBH (DE) | 2011-01-19 | — | — | EP | claimed |