Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 4/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.43 |
| ▸ | BBOX1 | O75936 | 3/20 | 0.43 |
| ▸ | RAD52 | P43351 | 3/20 | 0.40 |
| ▸ | POLR1A | O95602 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1028658 | 0.86 | EGLN1 (0.46) | FTOEGLN1BBOX1 | |
| SCHEMBL1033035 | 0.85 | EGLN1 (0.47) | FTOEGLN1BBOX1MEN1KMT2A | |
| SCHEMBL1028622 | 0.84 | EGLN1 (0.47) | FTOEGLN1BBOX1 | |
| SCHEMBL1033539 | 0.84 | EGLN1 (0.46) | FTOEGLN1BBOX1 | |
| SCHEMBL1032319 | 0.83 | THRA (0.38) | EGLN1RAD52 | |
| SCHEMBL1033428 | 0.83 | NPC1 (0.37) | EGLN1RAD52 | |
| SCHEMBL9524918 | 0.80 | RAD52 (0.42) | RAD52POLR1AMEN1KMT2A | |
| SCHEMBL522143 | 0.79 | EGLN1 (0.66) | FTOEGLN1BBOX1RAD52 | |
| SCHEMBL4081511 | 0.75 | EGLN1 (0.49) | FTOEGLN1BBOX1 | |
| SCHEMBL1033387 | 0.74 | FTO (0.46) | FTOEGLN1BBOX1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644336-B1 | NITROGEN-CONTAINING HETEROARYL COMPOUNDS AND THEIR USE IN INCREASING ENDOGENEOUS ERYTHROPOIETIN | FIBROGEN INC (US) | 2011-01-19 | — | — | EP | claimed |