Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Tetraphenylphosphonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 11/20 | 0.70 |
| ▸ | CA4 | P22748 | 2/20 | 0.70 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 10/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetraphenylphosphonium SCHEMBL21957806 | 0.95 | CA2 (0.62) | CA2CA4TSHRCES2CES1 | |
| Tetraphenylphosphonium SCHEMBL2000464 | 0.94 | CA2 (0.61) | CA2CA4TSHRCES2CES1 | |
| Tetraphenylphosphonium SCHEMBL7616105 | 0.90 | CA2 (0.57) | CA2CA4TSHRCES2CES1 | |
| Tetraphenylphosphonium SCHEMBL11233696 | 0.90 | CA2 (0.56) | CA2CA4TSHRCES2CES1 | |
| Tetraphenylphosphonium SCHEMBL7614263 | 0.87 | CA2 (0.53) | CA2CA4TSHRCES2CES1 | |
| Benzoic Acid SCHEMBL7872905 | 0.86 | CA2 (0.57) | CA2CA4CES2CES1ALDH1A1 | |
| Tetraphenylphosphonium SCHEMBL4388860 | 0.85 | CA2 (0.46) | CA2CA4TSHRCES2CES1 | |
| Benzoic Acid SCHEMBL11789341 | 0.85 | CA2 (0.94) | CA2CA4TSHRCES2CES1 | |
| Tetraphenylphosphonium SCHEMBL21957776 | 0.84 | ALDH1A1 (0.52) | CA2CA4TSHRCES2CES1 | |
| Tetraphenylphosphonium SCHEMBL1155888 | 0.83 | CA2 (0.44) | CA2CA4TSHRCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 188 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450403-B2 | Branched polycarbonate resin composition, and branched polycarbonate resin and molded product made using the same | CHEIL INDUSTRIES INC. (KR) | 2013-05-28 | — | — | US | claimed |
| US-20100160572-A1 | Branched Polycarbonate Resin Composition, and Branched Polycarbonate Resin and Molded Product Made Using the Same | CHEIL INDUSTRIES INC. (KR) | 2010-06-24 | — | — | US | claimed |
| US-7122613-B1 | Method for the production of polycarbonates | GENERAL ELECTRIC COMPANY (US) | 2006-10-17 | — | — | US | claimed |
| EP-1578840-A1 | METHOD FOR THE PRODUCTION OF POLYCARBONATES | General Electric Company (US) | 2005-09-28 | — | — | EP | claimed |
| WO-2004060963-A1 | METHOD FOR THE PRODUCTION OF POLYCARBONATES | GENERAL ELECTRIC COMPANY (US) | 2004-07-22 | — | — | WO | claimed |
| US-6316575-B1 | MELT TRANSESTERIFICATION OF DIOL COMPOUND AND CARBOANTE COMPOUND USING CATALYST COMPRISING A PHOSPHORUS-CONTAINING BASIC COMPOUND QUATERNARY PHOSPHONIUM SALT TO FORM POLYCARBONATE | IDEMITSU KOSAN CO., LTD. (JP) | 2001-11-13 | — | — | US | claimed |
| US-5153335-A | Reacting halophthalic anhydride and alkali metal salt with acid or acid derivative catalyst | OCCIDENTAL CHEMICAL CORPORATION (US) | 1992-10-06 | — | — | US | claimed |
| US-20260118767-A1 | REVERSE PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2026-04-30 | — | — | US | disclosed |
| US-20260044081-A1 | COMPOSITION FOR FORMING SILICON-CONTAINING RESIST FILM AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2026-02-12 | — | — | US | disclosed |
| EP-4692941-A2 | COMPOSITION FOR FORMING SILICON-CONTAINING RESIST FILM AND PATTERNING PROCESS | Shin-Etsu Chemical Co., Ltd. (JP) | 2026-02-11 | — | — | EP | disclosed |
| US-20250340697-A1 | METHOD FOR THE MANUFACTURE OF POLYCARBONATE | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2025-11-06 | — | — | US | disclosed |
| EP-4621486-A2 | POLYVALENT AMMONIUM SALT COMPOUND, COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM, AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2025-09-24 | — | — | EP | disclosed |
| US-20250289931-A1 | POLYVALENT AMMONIUM SALT COMPOUND, COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM, AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2025-09-18 | — | — | US | disclosed |
| EP-0826658-A1 | Catalyst for decarbonylation reaction | UBE INDUSTRIES, LTD. (JP) | 1998-03-04 | — | — | EP | disclosed |
| EP-0702044-A1 | Polycarbonate redistribution method | GENERAL ELECTRIC COMPANY (US) | 1996-03-20 | — | — | EP | disclosed |
| US-5459226-A | Melt extrusion in presence of tetraorganophosphonium carboxylate salt | GENERAL ELECTRIC COMPANY (US) | 1995-10-17 | — | — | US | disclosed |
| EP-0671428-A1 | Method for making polycarbonates | GENERAL ELECTRIC COMPANY (US) | 1995-09-13 | — | — | EP | disclosed |
| US-5412061-A | Polycarbonate melt condensation synthesis using a tetraorganophosphonium carboxylate salt catalyst | GENERAL ELECTRIC COMPANY (US) | 1995-05-02 | — | — | US | disclosed |
| US-5153335-A | Reacting halophthalic anhydride and alkali metal salt with acid or acid derivative catalyst | OCCIDENTAL CHEMICAL CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0460687-A2 | Process for the preparation of oxydiphthalic anhydride and acyloxyphthalic anhydrides | OCCIDENTAL CHEMICAL CORPORATION (US) | 1991-12-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250289931-A1 | POLYVALENT AMMONIUM SALT COMPOUND, COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM, AND PATTERNING PROCESS | ASH2L, PUF60, IDUA | CA2 1064/4885CA4 749/4885TSHR 3217/4885 |
| US-20260118767-A1 | REVERSE PATTERNING PROCESS | EFNA1, EPHA4, ETV6 | CA2 2902/4885CA4 281/4885TSHR 770/4885 |
| US-20260044081-A1 | COMPOSITION FOR FORMING SILICON-CONTAINING RESIST FILM AND PATTERNING PROCESS | SMC1A, SPOUT1, LBR | CA2 2105/4885CA4 1681/4885TSHR 446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.