Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMO | Q99835 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.38 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1515710 | 0.74 | S1PR5 (0.59) | L3MBTL1MAPTSMOALDH1A1NPC1 | |
| SCHEMBL3673844 | 0.73 | L3MBTL1 (0.49) | L3MBTL1MAPTSMOALDH1A1SMN1; SMN2 | |
| SCHEMBL2599737 | 0.70 | PIK3CA (0.58) | L3MBTL1MAPTSMOALDH1A1NPC1 | |
| SCHEMBL30486043 | 0.70 | MAPT (0.51) | L3MBTL1MAPTSMOALDH1A1SMN1; SMN2 | |
| SCHEMBL3917034 | 0.68 | NPC1 (0.56) | L3MBTL1MAPTSMOALDH1A1SMN1; SMN2 | |
| Isobutane SCHEMBL1801676 | 0.67 | MAPT (0.63) | L3MBTL1MAPTALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL14042688 | 0.67 | CA2 (0.59) | MAPTALDH1A1TDP1KDM4ELMNA | |
| SCHEMBL6026005 | 0.67 | MAPT (0.54) | L3MBTL1MAPTSMOALDH1A1SMN1; SMN2 | |
| SCHEMBL11289129 | 0.67 | MAPT (0.54) | L3MBTL1MAPTSMOALDH1A1SMN1; SMN2 | |
| SCHEMBL30008394 | 0.67 | ALDH1A1 (0.56) | L3MBTL1MAPTALDH1A1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120178747-A9 | Compositions and methods for bone formation and remodeling | ENZO LIFE SCIENCES, INC. | 2012-07-12 | — | — | US | disclosed |
| US-20100298308-A1 | Compositions and methods for bone formation and remodeling | ENZO THERAPEUTICS, INC. | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298308-A1 | Compositions and methods for bone formation and remodeling | DKK1, BMP6, LRP6 | L3MBTL1 562/4885MAPT 2666/4885SMO 795/4885 |
| US-20120178747-A9 | Compositions and methods for bone formation and remodeling | DKK1, BMP6, LRP6 | L3MBTL1 562/4885MAPT 2666/4885SMO 795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.