Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10326591 | 0.89 | MEN1 (0.30) | — | |
| SCHEMBL1171597 | 0.87 | — | — | |
| SCHEMBL10326589 | 0.86 | CA2 (0.31) | CA2 | |
| SCHEMBL11762156 | 0.84 | — | — | |
| SCHEMBL15739463 | 0.79 | PIK3CD (0.41) | CA2 | |
| SCHEMBL8439903 | 0.79 | PIK3CD (0.41) | CA2 | |
| SCHEMBL27796739 | 0.79 | PIK3CD (0.41) | CA2 | |
| SCHEMBL21401554 | 0.79 | PIK3CD (0.41) | CA2 | |
| SCHEMBL13135047 | 0.79 | PIK3CD (0.41) | CA2 | |
| SCHEMBL26210082 | 0.79 | PIK3CD (0.41) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9308274-B2 | Stabilized polymeric thiol reagents | NEKTAR THERAPEUTICS (US) | 2016-04-12 | — | — | US | disclosed |
| US-20140256951-A1 | STABILIZED POLYMERIC THIOL REAGENTS | NEKTAR THERAPEUTICS (US) | 2014-09-11 | — | — | US | disclosed |
| US-8765883-B2 | Stabilized polymeric thiol reagents | NEKTAR THERAPEUTICS (US) | 2014-07-01 | — | — | US | disclosed |
| US-20130280206-A1 | STABILIZED POLYMERIC THIOL REAGENTS | NEKTAR THERAPEUTICS | 2013-10-24 | — | — | US | disclosed |
| US-8492488-B2 | Stabilized polymeric thiol reagents | NEKTAR THERAPEUTICS (US) | 2013-07-23 | — | — | US | disclosed |
| US-20120258985-A1 | STABILIZED POLYMERIC THIOL REAGENTS | NEKTAR THERAPEUTICS (US) | 2012-10-11 | — | — | US | disclosed |
| US-8217123-B2 | Stabilized polymeric thiol reagents | NEKTAR THERAPEUTICS (US) | 2012-07-10 | — | — | US | disclosed |
| US-20110112277-A1 | Stabilized Polymeric Thiol Reagents | NEKTAR THERAPEUTICS (US) | 2011-05-12 | — | — | US | disclosed |
| US-7851565-B2 | For pegylation of biodrugs and drugs; for example, polyethylene glycol with pyridyldithioalkoxy end groups; allows target amino acid for attachment, to be cysteine instead of lysine which can inactive some peptide drugs | NEKTAR THERAPEUTICS (US) | 2010-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130280206-A1 | STABILIZED POLYMERIC THIOL REAGENTS | TST, STS, SCLY | CA2 4814/4885 |
| US-20110112277-A1 | Stabilized Polymeric Thiol Reagents | TST, CD44, MPST | CA2 4867/4885 |
| US-20140256951-A1 | STABILIZED POLYMERIC THIOL REAGENTS | TST, TTPA, MPST | CA2 4709/4885 |
| US-20120258985-A1 | STABILIZED POLYMERIC THIOL REAGENTS | TST, STS, CD44 | CA2 4813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.