Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10327450 | 0.91 | HPGD (0.42) | ALDH1A1LMNAMEN1KMT2AHPGD | |
| SCHEMBL12946791 | 0.89 | HPGD (0.51) | ALDH1A1LMNAMEN1KMT2AHPGD | |
| SCHEMBL10327490 | 0.83 | ALDH1A1 (0.53) | ALDH1A1LMNAMEN1KMT2APKM | |
| SCHEMBL3459036 | 0.83 | KMT2A (0.49) | ALDH1A1LMNAMEN1KMT2AHPGD | |
| SCHEMBL10327506 | 0.82 | SMN1; SMN2 (0.47) | ALDH1A1LMNAMEN1KMT2AHPGD | |
| SCHEMBL10327476 | 0.81 | SMN1; SMN2 (0.45) | ALDH1A1LMNAMEN1KMT2APKM | |
| SCHEMBL10327119 | 0.80 | LMNA (0.48) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10327048 | 0.75 | SMN1; SMN2 (0.55) | ALDH1A1LMNAMEN1KMT2AHPGD | |
| SCHEMBL964493 | 0.75 | ALDH1A1 (0.51) | ALDH1A1LMNAMEN1KMT2AHPGD | |
| SCHEMBL10327240 | 0.74 | SMN1; SMN2 (0.46) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678168-B1 | P70S6 KINASE MODULATORS AND METHOD OF USE | EXELIXIS INC (US) | 2012-07-11 | — | — | EP | disclosed |