Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | BUB1 | O43683 | 4/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | PDE1A | P54750 | 1/20 | 0.34 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.34 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11079732 | 0.86 | PDE3B (0.49) | KCNH2PDE3BPDE3ACRBNCYP19A1 | |
| SCHEMBL7450630 | 0.74 | PDE3B (0.61) | PDE3BPDE3ACRBNKMT2AMEN1 | |
| SCHEMBL9630168 | 0.73 | TDP2 (0.38) | CRBNCHEK1 | |
| Hydrochloric Acid SCHEMBL10756530 | 0.73 | PDE3B (0.60) | PDE3BPDE3ACRBNKMT2AMEN1 | |
| SCHEMBL11008299 | 0.73 | SRD5A1 (0.42) | PDE3BPDE3ACRBNKMT2ACYP19A1 | |
| SCHEMBL11083179 | 0.72 | CYP11B1 (0.52) | PDE3BPDE3ACRBNCYP19A1 | |
| SCHEMBL11084887 | 0.71 | ALDH1A1 (0.46) | CRBNKMT2ADDB1KDM4EMEN1 | |
| Senazodan SCHEMBL1652002 | 0.71 | KCNH2 (1.00) | KCNH2PDE3BPDE3AKMT2APDE2A | |
| Senazodan SCHEMBL1649599 | 0.70 | KCNH2 (0.97) | KCNH2PDE3BPDE3AKMT2APDE2A | |
| Senazodan SCHEMBL4519202 | 0.70 | KCNH2 (0.97) | KCNH2PDE3BPDE3AKMT2APDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2059571-A | — | — | None | — | — | JP | disclosed |
| JP-H0259571-A | PYRIDONE DERIVATIVE OR SALTS THEREOF | MITSUBISHI KASEI CORP | 1990-02-28 | — | — | JP | disclosed |