SCHEMBL10340337

SCHEMBL10340337

F[B-](F)(F)F.N#[N+]c1ccc(S(=O)(=O)NCC(=O)O)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 3/20 0.59
MMP12 P39900 2/20 0.59
GAA P10253 1/20 0.59
MMP2 P08253 2/20 0.52
MMP3 P08254 2/20 0.52
MMP7 P09237 2/20 0.52
MMP9 P14780 2/20 0.52
MMP13 P45452 2/20 0.52
APEX1 P27695 1/20 0.49
KAT6A Q92794 1/20 0.46
KDM4E B2RXH2 2/20 0.46
TDP1 Q9NUW8 1/20 0.46
KMT2A Q03164 1/20 0.46
GRIN2D O15399 1/20 0.45
GRIN3B O60391 1/20 0.45
ALDH1A1 P00352 1/20 0.45
GRIN1 Q05586 1/20 0.45
GRIN2A Q12879 1/20 0.45
GRIN2B Q13224 1/20 0.45
GRIN2C Q14957 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10883426 0.94 MMP1 (0.61) MMP1MMP12GAAMMP2MMP3
SCHEMBL2990778 0.76 MMP1 (0.67) MMP1MMP12GAAMMP2MMP3
SCHEMBL10890150 0.74 MMP1 (1.00) MMP1MMP12GAAMMP2MMP3
SCHEMBL359770 0.73 MMP1 (0.79) MMP1MMP12GAAMMP2MMP3
SCHEMBL10340484 0.73 ALDH1A1 (0.51) GAAKDM4EKMT2AALDH1A1
SCHEMBL10340463 0.73 KDM4E (0.54) KDM4EALDH1A1
SCHEMBL19392592 0.73 MMP1 (0.67) MMP1MMP12GAAMMP2MMP3
SCHEMBL760439 0.73 MMP1 (0.67) MMP1MMP12GAAMMP2MMP3
SCHEMBL1228868 0.73 MMP1 (0.67) MMP1MMP12GAAMMP2MMP3
SCHEMBL7671414 0.73 MEP1B (0.73) MMP1MMP12GAAMMP2MMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0158507-B1 REAGENT COMPOSITION, DRY ELEMENT AND METHOD FOR DETERMINATION OF TOTAL BILIRUBIN EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1990-12-05 EP claimed
EP-0158507-A2 Reagent composition, dry element and method for determination of total bilirubin EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1985-10-16 EP claimed
EP-0158507-B1 REAGENT COMPOSITION, DRY ELEMENT AND METHOD FOR DETERMINATION OF TOTAL BILIRUBIN EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1990-12-05 EP disclosed
EP-0158506-B1 METHOD AND APPARATUS FOR DETERMINATION OF AN ANALYTE AND METHOD OF CALIBRATING SUCH APPARATUS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1990-02-28 EP disclosed
US-4627014-A Chemical analyzer for the determination of an analyte EASTMAN KODAK COMPANY (US) 1986-12-02 US disclosed
EP-0087599-B1 DIAZONIUM SALTS AND REAGENTS FOR BILIRUBIN ASSAY EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1986-11-05 EP disclosed
US-4548905-A Reagent composition, dry element and method for determination of total bilirubin EASTMAN KODAK COMPANY (US) 1985-10-22 US disclosed
EP-0158507-A2 Reagent composition, dry element and method for determination of total bilirubin EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1985-10-16 EP disclosed
EP-0158506-A2 Method and apparatus for determination of an analyte and method of calibrating such apparatus EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1985-10-16 EP disclosed
US-4468467-A Diazonium salt for bilirubin assay EASTMAN KODAK COMPANY (US) 1984-08-28 US disclosed
EP-0087599-A1 Diazonium salts and reagents for bilirubin assay EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1983-09-07 EP disclosed