Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 4/20 | 0.35 |
| ▸ | CES1 | P23141 | 3/20 | 0.34 |
| ▸ | PPARG | P37231 | 6/20 | 0.33 |
| ▸ | PPARD | Q03181 | 6/20 | 0.33 |
| ▸ | PPARA | Q07869 | 6/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.33 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TLR2 | O60603 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | FABP4 | P15090 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL13835081 | 1.00 | CES2 (0.35) | CES2CES1PPARGPPARDPPARA | |
| SCHEMBL2921196 | 0.95 | CES2 (0.38) | CES2CES1GGPS1 | |
| SCHEMBL2923879 | 0.95 | CES2 (0.38) | CES2CES1GGPS1 | |
| SCHEMBL10340646 | 0.81 | BBOX1 (0.39) | — | |
| SCHEMBL3903140 | 0.76 | ODC1 (0.32) | PDE3A | |
| Acetic Acid SCHEMBL4198026 | 0.75 | SMPD1 (0.40) | CES2CES1PPARGPPARDPPARA | |
| SCHEMBL4126709 | 0.74 | BBOX1 (0.36) | CES2CES1TSHRMEN1KMT2A | |
| SCHEMBL11787297 | 0.72 | GPR84 (0.35) | CES2CES1PPARDGPR84FFAR1 | |
| SCHEMBL20853667 | 0.72 | CES2 (0.41) | CES2CES1GGPS1 | |
| SCHEMBL3295870 | 0.71 | CES2 (0.38) | CES2CES1PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2247114-A | — | — | None | — | — | JP | disclosed |
| US-11390728-B2 | Cellulose-containing resin composition and cellulosic ingredient | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2022-07-19 | — | — | US | disclosed |
| US-20210198455-A1 | Cellulose-Containing Resin Composition and Cellulosic Ingredient | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2021-07-01 | — | — | US | disclosed |
| US-20210162166-A1 | SOLID FREEFORM FABRICATION PRODUCT AND METHOD OF MANUFACTURING SOLID FREEFORM FABRICATION PRODUCT | RICOH COMPANY, LTD. (JP) | 2021-06-03 | — | — | US | disclosed |
| EP-3827966-A1 | SOLID FREEFORM FABRICATION PRODUCT AND METHOD OF MANUFACTURING SOLID FREEFORM FABRICATION PRODUCT | Ricoh Company, Ltd. (JP) | 2021-06-02 | — | — | EP | disclosed |
| US-10950143-B2 | Hydrogel structure, blood vessel, internal organ model, practice tool for medical procedure, and method of manufacturing the hydrogel structure | RICOH COMPANY, LTD. (JP) | 2021-03-16 | — | — | US | disclosed |
| EP-3291208-B1 | HYDROGEL STRUCTURE, BLOOD VESSEL, INTERNAL ORGAN MODEL, PRACTICE TOOL FOR MEDICAL PROCEDURE, AND METHOD OF MANUFACTURING THE HYDROGEL STRUCTURE | RICOH CO LTD (JP) | 2020-09-30 | — | — | EP | disclosed |
| US-10007207-B2 | Liquid developer and method for manufacturing the same | Konica Minolta, Inc. (JP) | 2018-06-26 | — | — | US | disclosed |
| EP-3291208-A1 | HYDROGEL STRUCTURE, BLOOD VESSEL, INTERNAL ORGAN MODEL, PRACTICE TOOL FOR MEDICAL PROCEDURE, AND METHOD OF MANUFACTURING THE HYDROGEL STRUCTURE | Ricoh Company, Ltd. (JP) | 2018-03-07 | — | — | EP | disclosed |
| US-20180061279-A1 | HYDROGEL STRUCTURE, BLOOD VESSEL, INTERNAL ORGAN MODEL, PRACTICE TOOL FOR MEDICAL PROCEDURE, AND METHOD OF MANUFACTURING THE HYDROGEL STRUCTURE | RICOH COMPANY, LTD. (JP) | 2018-03-01 | — | — | US | disclosed |
| WO-2006132433-A1 | INK JET INK, METHOD OF PRODUCING INK JET INK, INK JET RECORDING METHOD, INK CARTRIDGE, AND YELLOW INK | CANON KABUSHIKI KAISHA (JP) | 2006-12-14 | — | — | WO | disclosed |
| US-20060165636-A1 | Hair treatment composition and hair cosmetic for damaged hair | MEIJI SEIKA KAISHA, LTD. (JP) | 2006-07-27 | — | — | US | disclosed |
| EP-1602354-A1 | HAIR TREATMENT COMPOSITION AND HAIR COSMETIC FOR DAMAGED HAIR | Meiji Seika Kaisha, Ltd. (JP) | 2005-12-07 | — | — | EP | disclosed |
| US-6610775-B1 | White polyamide fibers; copolymer of a polyfluoroalkyl acrylate and an acrylate having hydroxyalkyl ester group where hydroxy group and double bond are separated by at least 7 covalent bonds so the Rf group receives no steric hindrance | ASAHI GLASS COMPANY, LIMITED (JP) | 2003-08-26 | — | — | US | disclosed |
| US-6607736-B2 | Endermic liniment comprising diethoxy ethyl succinate and humectant | SHISEIDO COMPANY, LTD. (JP) | 2003-08-19 | — | — | US | disclosed |
| US-20030091603-A1 | Skin preparations for external use | SHISEIDO COMPANY, LTD. (JP) | 2003-05-15 | — | — | US | disclosed |
| EP-1174484-A1 | WATER-AND-OIL REPELLANT COMPOSITION AND PROCESS FOR PRODUCING THE SAME | ASAHI GLASS COMPANY LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| EP-1153602-A1 | SKIN PREPARATIONS FOR EXTERNAL USE | SHISEIDO COMPANY LIMITED (JP) | 2001-11-14 | — | — | EP | disclosed |
| JP-2000072630-A | SHAMPOO COMPOSITION | KOSE CORP | 2000-03-07 | — | — | JP | disclosed |
| JP-H02247114-A | SHAMPOO COMPOSITION | HOECHST JAPAN LTD | 1990-10-02 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030091603-A1 | Skin preparations for external use | CUTA, POLR1C, ACMSD | ESR1 995/4885CES2 196/4885CES1 496/4885 |
| US-20060165636-A1 | Hair treatment composition and hair cosmetic for damaged hair | CUTA, COL14A1, PRKDC | ESR1 4754/4885CES2 4498/4885CES1 4802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.