Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.34 |
| ▸ | PNLIP | P16233 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10994173 | 0.86 | ALDH1A1 (0.44) | GRM4MEN1KMT2ATNIKALDH1A1 | |
| SCHEMBL10344850 | 0.78 | TRPA1 (0.48) | ALDH1A1CYP1A2CYP2C9CYP2C19HCAR1 | |
| SCHEMBL10345191 | 0.78 | CA12 (0.46) | ALDH1A1CYP1A2GPR84HCAR1TRPA1 | |
| SCHEMBL21449750 | 0.73 | TRPA1 (0.35) | CYP1A2GPR84TRPA1 | |
| SCHEMBL10345206 | 0.73 | CA12 (0.50) | MEN1KMT2ACYP1A2HCAR1GAA | |
| SCHEMBL15934252 | 0.73 | HCAR1 (0.40) | GRM4ALDH1A1HPGDHCAR1GAA | |
| SCHEMBL9187399 | 0.72 | GPR84 (0.51) | GPR84 | |
| SCHEMBL9544710 | 0.72 | L3MBTL1 (0.55) | MEN1KMT2AALDH1A1L3MBTL1HPGD | |
| SCHEMBL11526524 | 0.71 | ALDH1A1 (0.50) | ALDH1A1CYP1A2L3MBTL1CYP2C9HPGD | |
| SCHEMBL4410502 | 0.71 | MAPT (0.51) | MEN1KMT2AALDH1A1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0144195-B1 | SQUARAINE COMPOSITIONS | XEROX CORPORATION (US) | 1990-04-11 | — | — | EP | disclosed |
| US-4552822-A | Photoconductive devices with hydroxy containing squaraine compositions | XEROX CORPORATION (US) | 1985-11-12 | — | — | US | disclosed |
| US-4524218-A | FROM SQUARIC ACID AN AROMATIC AMINE, AND A PHENOL OR PHENOL SWUARINE | XEROX CORPORATION (US) | 1985-06-18 | — | — | US | disclosed |
| EP-0144195-A2 | Squaraine compositions | XEROX CORPORATION (US) | 1985-06-12 | — | — | EP | disclosed |