Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | LIPE | Q05469 | 1/20 | 0.43 |
| ▸ | EDNRA | P25101 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28638978 | 0.83 | L3MBTL1 (0.52) | HPGDCACNA1BL3MBTL1ALDH1A1MAPK14 | |
| SCHEMBL10675484 | 0.82 | LMNA (0.54) | LTA4HMAPK14LMNA | |
| SCHEMBL7747383 | 0.82 | LTA4H (0.58) | CACNA1BALDH1A1RECQLCACNA1HLTA4H | |
| SCHEMBL10960140 | 0.81 | ALDH1A1 (0.63) | HPGDL3MBTL1ALDH1A1RECQLLTA4H | |
| SCHEMBL584253 | 0.79 | CYP3A4 (0.58) | ALDH1A1RECQLLTA4H | |
| SCHEMBL10348407 | 0.79 | CACNA1B (0.44) | HPGDCACNA1BLIPECACNA1HLTA4H | |
| SCHEMBL12676015 | 0.76 | CYP3A4 (0.54) | ALDH1A1RECQLLTA4H | |
| SCHEMBL2350644 | 0.76 | AR (0.47) | L3MBTL1ALDH1A1RECQLARLMNA | |
| SCHEMBL9589613 | 0.76 | AR (0.51) | CACNA1BL3MBTL1ALDH1A1ARMAPK14 | |
| SCHEMBL28672016 | 0.76 | NCOA1 (0.62) | ALDH1A1SCN9ACYP19A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001036371-A1 | CARBONIC ACID DERIVATIVES AND THEIR USE AS ECTOPARASITICIDAL COMPOSITION | NOVARTIS AG (CH) | 2001-05-25 | — | — | WO | disclosed |