Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK2 | P19525 | 2/20 | 0.53 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.53 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.53 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | HTT | P42858 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | CASP3 | P42574 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | MAP3K5 | Q99683 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | CASP1 | P29466 | 4/20 | 0.37 |
| ▸ | CASP7 | P55210 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8171875 | 0.70 | EIF2AK2 (1.00) | EIF2AK2MAPK12MAPK13MAPK11MAPK14 | |
| SCHEMBL30821077 | 0.70 | EIF2AK2 (0.67) | EIF2AK2MAPK12MAPK13MAPK11MAPK14 | |
| SCHEMBL8176664 | 0.70 | EIF2AK2 (0.66) | EIF2AK2MAPK12MAPK13MAPK11MAPK14 | |
| SCHEMBL11120339 | 0.68 | EIF2AK2 (0.62) | EIF2AK2MAPK12MAPK13MAPK11MAPK14 | |
| Anthraquinone SCHEMBL11789994 | 0.67 | KMT2A (0.56) | LMNAKMT2AHTTALDH1A1L3MBTL1 | |
| SCHEMBL10349467 | 0.66 | EIF2AK2 (0.56) | EIF2AK2MAPK12MAPK13MAPK11MAPK14 | |
| SCHEMBL4846358 | 0.64 | EIF2AK2 (0.53) | EIF2AK2MAPK12MAPK13MAPK11MAPK14 | |
| SCHEMBL8172006 | 0.62 | EIF2AK2 (0.54) | EIF2AK2MAPK12MAPK13MAPK11MAPK14 | |
| SCHEMBL628691 | 0.61 | ADRA2A (0.43) | LMNAKMT2AALDH1A1MEN1CASP1 | |
| SCHEMBL16297128 | 0.61 | LMNA (0.77) | LMNAKMT2AHTTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497809-B1 | 1,4-BIS(ALKYLAMINO)-2,3-DIAZA-ANTHRACENE-9,10-DIONES | BOEHRINGER MANNHEIM ITALIA (IT) | 1995-06-28 | — | — | EP | disclosed |
| WO-1991006540-A1 | 1,4-BIS(ALKYLAMINO)-2,3-DIAZA-ANTHRACENE-9,10-DIONES | BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) | 1991-05-16 | — | — | WO | disclosed |