Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 9/20 | 0.50 |
| ▸ | ACLY | P53396 | 2/20 | 0.39 |
| ▸ | ACACA | Q13085 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.35 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL568813 | 0.81 | HSD11B1 (0.50) | HSD11B1ACLYACACAESR2PTGS1 | |
| SCHEMBL982765 | 0.78 | ACLY (0.63) | HSD11B1ACLYACACAESR2PTGS1 | |
| SCHEMBL1878720 | 0.78 | ACLY (0.63) | HSD11B1ACLYACACAESR2PTGS1 | |
| SCHEMBL13801861 | 0.78 | ACLY (0.63) | HSD11B1ACLYACACAESR2PTGS1 | |
| SCHEMBL14047057 | 0.78 | ACLY (0.63) | HSD11B1ACLYACACAESR2PTGS1 | |
| SCHEMBL13420256 | 0.78 | ACLY (0.63) | HSD11B1ACLYACACAESR2PTGS1 | |
| SCHEMBL12152345 | 0.78 | ACLY (0.63) | HSD11B1ACLYACACAESR2PTGS1 | |
| SCHEMBL14520017 | 0.78 | ACLY (0.63) | HSD11B1ACLYACACAESR2PTGS1 | |
| SCHEMBL1878721 | 0.78 | ACLY (0.63) | HSD11B1ACLYACACAESR2PTGS1 | |
| SCHEMBL11408854 | 0.78 | ACLY (0.63) | HSD11B1ACLYACACAESR2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0166542-B1 | TRITERPENYL ESTERS OF ORGANIC ACIDS, PROCESS FOR THEIR PRODUCTION, AND HYPOLIPIDEMIC AGENTS COMPOSED OF THEM | AMANO PHARMACEUTICAL CO., LTD. (JP) | 1990-08-08 | — | — | EP | claimed |
| EP-0166542-B1 | TRITERPENYL ESTERS OF ORGANIC ACIDS, PROCESS FOR THEIR PRODUCTION, AND HYPOLIPIDEMIC AGENTS COMPOSED OF THEM | AMANO PHARMACEUTICAL CO., LTD. (JP) | 1990-08-08 | — | — | EP | disclosed |
| US-4748161-A | Triterpenyl esters of organic acids and hypolipidemic agents composed of them | AMANO PHARMACEUTICAL CO., LTD. (JP) | 1988-05-31 | — | — | US | disclosed |
| EP-0166542-A2 | Triterpenyl esters of organic acids, process for their production, and hypolipidemic agents composed of them | AMANO PHARMACEUTICAL CO., LTD. (JP) | 1986-01-02 | — | — | EP | disclosed |