SCHEMBL568813

SCHEMBL568813

C=C(CC[C@@H](C)[C@H]1CC[C@@]2(C)[C@@H]3CC[C@H]4C(C)(C)CCC(O)[C@@]45C[C@@]35CC[C@]12C)C(C)C

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ HSD11B1 P28845 8/20 0.50
▸ ACLY P53396 2/20 0.46
▸ ACACA Q13085 2/20 0.46
▸ PTPN11 Q06124 1/20 0.43
▸ HSD11B2 P80365 1/20 0.38
▸ ESR2 Q92731 1/20 0.38
▸ PTGS1 P23219 1/20 0.37
▸ PTGS2 P35354 1/20 0.37
▸ NR1H3 Q13133 1/20 0.37
▸ PTPN1 P18031 3/20 0.37
▸ CYP2C19 P33261 1/20 0.35
▸ HIF1A Q16665 1/20 0.35
▸ EBP Q15125 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1874653 0.86 ACLY (0.48) HSD11B1ACLYACACAPTPN11HSD11B2
SCHEMBL1878720 0.84 ACLY (0.63) HSD11B1ACLYACACAPTPN11HSD11B2
SCHEMBL14520017 0.84 ACLY (0.63) HSD11B1ACLYACACAPTPN11HSD11B2
SCHEMBL13801861 0.84 ACLY (0.63) HSD11B1ACLYACACAPTPN11HSD11B2
SCHEMBL14047057 0.84 ACLY (0.63) HSD11B1ACLYACACAPTPN11HSD11B2
SCHEMBL12152345 0.84 ACLY (0.63) HSD11B1ACLYACACAPTPN11HSD11B2
SCHEMBL13420256 0.84 ACLY (0.63) HSD11B1ACLYACACAPTPN11HSD11B2
SCHEMBL982765 0.84 ACLY (0.63) HSD11B1ACLYACACAPTPN11HSD11B2
SCHEMBL1878721 0.84 ACLY (0.63) HSD11B1ACLYACACAPTPN11HSD11B2
SCHEMBL13455191 0.84 ACLY (0.63) HSD11B1ACLYACACAPTPN11HSD11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 675 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117460535-A Composition based on monoacylglycerols and free fatty acids, method for the production and use thereof 格雷科斯生物股份有限公司 2024-01-26 — — CN claimed
CN-110300575-B Extract of celastrus orbiculatus rattan, cosmetic composition comprising same and cosmetic use thereof ISP投资有限公司 2022-11-15 — — CN claimed
EP-2767172-B1 FAT COMPOSITION KAO CORP (JP) 2022-06-08 — — EP claimed
EP-2656737-B1 FAT AND/OR OIL COMPOSITION KAO CORP (JP) 2019-04-24 — — EP claimed
EP-2641475-B1 OIL OR FAT COMPOSITION KAO CORP (JP) 2018-03-28 — — EP claimed
EP-2749177-B1 OIL/FAT COMPOSITION KAO CORP (JP) 2017-03-29 — — EP claimed
EP-3120854-A1 CYCLOARTENOL-CONTAINING COMPOSITION Kao Corporation (JP) 2017-01-25 — — EP claimed
US-20170014430-A1 Cycloartenol-Containing Composition KAO CORPORATION (JP) 2017-01-19 — — US claimed
EP-2749176-B1 OIL/FAT COMPOSITION KAO CORP (JP) 2016-08-10 — — EP claimed
US-9399041-B2 Fat composition KAO CORPORATION (JP) 2016-07-26 — — US claimed
WO-2004095926-A2 TREATMENT OF PLANTS AND PLANT PROPAGATION MATERIALS WITH AN ANTIOXIDANT TO IMPROVE PLANT HEALTH AND/OR YIELD MONSANTO TECHNOLOGY, LLC (US) 2004-11-11 — — WO claimed
WO-2004050208-A1 METHOD OF EXTRACT COMPOSITION CONTROL IN PEAT EXTRACTION, PEAT EXTRACT, AND USE OF PEAT EXTRACT AROMTECH LTD (FI) 2004-06-17 — — WO claimed
EP-1426028-A1 Method of extract composition control in peat extraction, peat extract, and use of peat extract Aromtech Ltd (FI) 2004-06-09 — — EP claimed
JP-2004504291-A — — 2004-02-12 — — JP claimed
US-20030195367-A1 Method for preparing a fatty substance ester and use thereof in pharmaceutics, cosmetics or food industry LABORATOIRES EXPANSCIENCE (FR) 2003-10-16 — — US claimed
EP-1301460-A1 METHOD FOR PREPARING A FATTY SUBSTANCE ESTER AND USE THEREOF IN PHARMACEUTICS, COSMETICS OR FOOD INDUSTRY Laboratoires Expanscience (FR) 2003-04-16 — — EP claimed
WO-2002006205-B1 METHOD FOR PREPARING A FATTY SUBSTANCE ESTER AND USE THEREOF IN PHARMACEUTICS, COSMETICS OR FOOD INDUSTRY PHARMASCIENCE LAB (FR) 2002-03-21 — — WO claimed
WO-2002006205-A1 METHOD FOR PREPARING A FATTY SUBSTANCE ESTER AND USE THEREOF IN PHARMACEUTICS, COSMETICS OR FOOD INDUSTRY LABORATOIRES EXPANSCIENCE (FR) 2002-01-24 — — WO claimed
US-4748161-A Triterpenyl esters of organic acids and hypolipidemic agents composed of them AMANO PHARMACEUTICAL CO., LTD. (JP) 1988-05-31 — — US claimed
EP-0166542-A2 Triterpenyl esters of organic acids, process for their production, and hypolipidemic agents composed of them AMANO PHARMACEUTICAL CO., LTD. (JP) 1986-01-02 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030195367-A1 Method for preparing a fatty substance ester and use thereof in pharmaceutics, cosmetics or food industry LSS, CYP51A1, CYP46A1 HSD11B1 8/4885ACLY 2551/4885ACACA 1616/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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