Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TPMT | P51580 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.34 |
| ▸ | FABP4 | P15090 | 1/20 | 0.34 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,6-Hexanediol SCHEMBL17819100 | 0.90 | KDM4E (0.35) | KDM4EL3MBTL1HPGDLMNAMEN1 | |
| SCHEMBL17819098 | 0.86 | TAS1R3 (0.36) | KDM4EL3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL20636994 | 0.81 | NPSR1 (0.40) | KDM4EL3MBTL1HPGDLMNAMEN1 | |
| SCHEMBL1035817 | 0.80 | KDM4E (0.37) | KDM4EL3MBTL1HPGDLMNAMEN1 | |
| SCHEMBL1037385 | 0.80 | KMT2A (0.46) | KDM4EL3MBTL1HPGDLMNAMEN1 | |
| SCHEMBL1037277 | 0.79 | LMNA (0.37) | KDM4EL3MBTL1HPGDLMNAMEN1 | |
| SCHEMBL1034451 | 0.79 | NLRP3 (0.45) | KDM4EL3MBTL1HPGDLMNAMEN1 | |
| SCHEMBL1037184 | 0.78 | LMNA (0.38) | KDM4EL3MBTL1HPGDLMNAMEN1 | |
| SCHEMBL13412090 | 0.76 | KDM4E (0.41) | KDM4EL3MBTL1HPGDLMNAMEN1 | |
| SCHEMBL21111136 | 0.76 | KMT2A (0.39) | KDM4EL3MBTL1HPGDLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10023675-B2 | Polymer nanoparticles | ETH ZUERICH (CH) | 2018-07-17 | — | — | US | disclosed |
| US-10023675-B2 | Polymer nanoparticles | ETH ZUERICH (CH) | 2018-07-17 | — | — | US | disclosed |
| US-10023675-B2 | Polymer nanoparticles | ETH ZUERICH (CH) | 2018-07-17 | — | — | US | disclosed |
| EP-2630163-B1 | ULTRA FAST PROCESS FOR THE PREPARATION OF POLYMER NANOPARTICLES | MAX PLANCK GESELLSCHAFT (DE) | 2018-05-16 | — | — | EP | disclosed |
| US-20160024241-A1 | POLYMER NANOPARTICLES | ETH ZUERICH (CH) | 2016-01-28 | — | — | US | disclosed |
| US-20160024241-A1 | POLYMER NANOPARTICLES | ETH ZUERICH (CH) | 2016-01-28 | — | — | US | disclosed |
| US-20160024241-A1 | POLYMER NANOPARTICLES | ETH ZUERICH (CH) | 2016-01-28 | — | — | US | disclosed |
| US-9181358-B2 | Polymer nanoparticles | ETH ZUERICH (CH) | 2015-11-10 | — | — | US | disclosed |
| US-9181358-B2 | Polymer nanoparticles | ETH ZUERICH (CH) | 2015-11-10 | — | — | US | disclosed |
| US-9181358-B2 | Polymer nanoparticles | ETH ZUERICH (CH) | 2015-11-10 | — | — | US | disclosed |
| US-20120115963-A1 | POLYMER NANOPARTICLES | ETH ZUERICH (CH) | 2012-05-10 | — | — | US | disclosed |
| US-20120115963-A1 | POLYMER NANOPARTICLES | ETH ZUERICH (CH) | 2012-05-10 | — | — | US | disclosed |
| US-20120115963-A1 | POLYMER NANOPARTICLES | ETH ZUERICH (CH) | 2012-05-10 | — | — | US | disclosed |
| WO-2012052148-A1 | ULTRA FAST PROCESS FOR THE PREPARATION OF POLYMER NANOPARTICLES | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2012-04-26 | — | — | WO | disclosed |
| EP-1814891-B1 | BISACYLPHOSPHANES AND THEIR USE AS PHOTOINITIATORS; PROCESS FOR PREPARING ACYLPHOSPHANES | BASF SE (DE) | 2011-01-26 | — | — | EP | disclosed |
| WO-2010121387-A1 | POLYMER NANOPARTICLES | ETH Zürich (CH) | 2010-10-28 | — | — | WO | disclosed |
| US-7687657-B2 | Process for preparing acylphosphanes and derivatives thereof | CIBA SPECIALITY CHEMICALS CORPORATION (US) | 2010-03-30 | — | — | US | disclosed |
| US-20080004464-A1 | Process for Preparing Acylphosphanes and Derivatives Thereof | IGM GROUP B.V. (NL) | 2008-01-03 | — | — | US | disclosed |
| EP-1814891-A1 | PROCESS FOR PREPARING ACYLPHOSPHANES AND DERIVATIVES THEREOF | Ciba Specialty Chemicals Holding Inc. (CH) | 2007-08-08 | — | — | EP | disclosed |
| WO-2006056541-A1 | PROCESS FOR PREPARING ACYLPHOSPHANES AND DERIVATIVES THEREOF | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2006-06-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004464-A1 | Process for Preparing Acylphosphanes and Derivatives Thereof | ME2, ME3, MEP1A | KDM4E 2950/4885L3MBTL1 1140/4885HPGD 1061/4885 |
| US-20160024241-A1 | POLYMER NANOPARTICLES | POLQ, POLN, POLA1 | KDM4E 4562/4885L3MBTL1 3134/4885HPGD 908/4885 |
| US-10023675-B2 | Polymer nanoparticles | POLQ, POLN, POLA1 | KDM4E 4562/4885L3MBTL1 3134/4885HPGD 908/4885 |
| US-20120115963-A1 | POLYMER NANOPARTICLES | POLQ, POLN, POLA1 | KDM4E 4562/4885L3MBTL1 3134/4885HPGD 908/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.