Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRB1ADRB2ADRB3CYP11B1DPP4FGFR1FGFR2FGFR3FGFR4HRH1JAK1JAK2JAK3KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITNAOPRD1OPRK1OPRM1PPDGFRBPIK3CDSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASMOTYK2polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Adenine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 known ✓ | P11362 | 1/20 | 0.35 |
| ▸ | PI4KA | P42356 | 4/20 | 0.40 |
| ▸ | PI4K2B | Q8TCG2 | 4/20 | 0.40 |
| ▸ | PI4K2A | Q9BTU6 | 4/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.40 |
| ▸ | XDH | P47989 | 2/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PNP | P00491 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adenine SCHEMBL338435 | 1.00 | PI4KA (0.40) | PI4KAPI4K2BPI4K2API4KBXDH | |
| Adenine SCHEMBL2411187 | 0.98 | PI4KA (0.39) | PI4KAPI4K2BPI4K2API4KBXDH | |
| Adenine SCHEMBL8509836 | 0.98 | PI4KA (0.39) | PI4KAPI4K2BPI4K2API4KBXDH | |
| Adenine SCHEMBL4908366 | 0.96 | PI4KA (0.38) | PI4KAPI4K2BPI4K2API4KBXDH | |
| Adenine SCHEMBL9275554 | 0.93 | PI4KA (0.38) | PI4KAPI4K2BPI4K2API4KBXDH | |
| Adenine SCHEMBL385841 | 0.88 | PI4KA (0.45) | PI4KAPI4K2BPI4K2API4KBXDH | |
| Adenine SCHEMBL8110 | 0.88 | PI4KA (0.48) | PI4KAPI4K2BPI4K2API4KBXDH | |
| Adenine SCHEMBL3414603 | 0.88 | PI4KA (0.48) | PI4KAPI4K2BPI4K2API4KBXDH | |
| Adenine SCHEMBL3416954 | 0.88 | PI4KA (0.48) | PI4KAPI4K2BPI4K2API4KBXDH | |
| Adenine SCHEMBL3413247 | 0.88 | PI4KA (0.48) | PI4KAPI4K2BPI4K2API4KBXDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 204 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11129930-B2 | System and method for obtaining a cellular sample enriched with defined cells such as platelet rich plasma (PRP) | ESTAR TECHNOLOGIES LTD (IL) | 2021-09-28 | — | — | US | claimed |
| EP-1877757-B1 | METHOD FOR USING AN ALL SOLID-STATE FLUOROMETER IN MONITORING AND CONTROLLING CHEMICALS IN WATER | NALCO CO (US) | 2021-03-10 | — | — | EP | claimed |
| US-20200215254-A1 | SYSTEM AND METHOD FOR OBTAINING A CELLULAR SAMPLE ENRICHED WITH DEFINED CELLS SUCH AS PLATELET RICH PLASMA (PRP) | ESTAR TECHNOLOGIES LTD (IL) | 2020-07-09 | — | — | US | claimed |
| CN-103717753-B | System and method for genetic and biological analysis | 吉纳普赛斯股份有限公司 | 2016-12-07 | — | — | CN | claimed |
| US-20140329699-A1 | SYSTEMS AND METHODS FOR HIGH EFFICIENCY ELECTRONIC SEQUENCING AND DETECTION | OXFORD FINANCE LLC, AS COLLATERAL AGENT | 2014-11-06 | — | — | US | claimed |
| CN-104105797-A | System and method for efficient electronic sequencing and detection | GENAPSYS INC | 2014-10-15 | — | — | CN | claimed |
| EP-2785868-A1 | SYSTEMS AND METHODS FOR HIGH EFFICIENCY ELECTRONIC SEQUENCING AND DETECTION | Genapsys Inc. (US) | 2014-10-08 | — | — | EP | claimed |
| CN-103717753-A | System and method for genetic and biological analysis | GENAPSYS INC | 2014-04-09 | — | — | CN | claimed |
| WO-2013082619-A1 | SYSTEMS AND METHODS FOR HIGH EFFICIENCY ELECTRONIC SEQUENCING AND DETECTION | GENAPSYS, INC. (US) | 2013-06-06 | — | — | WO | claimed |
| WO-2012166742-A2 | SYSTEMS AND METHODS FOR GENETIC AND BIOLOGICAL ANALYSIS | GENAPSYS, INC. (US) | 2012-12-06 | — | — | WO | claimed |
| EP-1877757-A2 | METHOD FOR USING AN ALL SOLID-STATE FLUOROMETER IN MONITORING AND CONTROLLING CHEMICALS IN WATER | Nalco Company (US) | 2008-01-16 | — | — | EP | claimed |
| WO-2006118876-A2 | METHOD FOR USING AN ALL SOLID-STATE FLUOROMETER IN MONITORING AND CONTROLLING CHEMICALS IN WATER | NALCO COMPANY (US) | 2006-11-09 | — | — | WO | claimed |
| US-20060246595-A1 | Method for using an all solid-state fluorometer in monitoring and controlling chemicals in water | ECOLAB USA INC. | 2006-11-02 | — | — | US | claimed |
| EP-4705328-A2 | METHODS AND PLATFORM RELATED TO FLUORESCENT PROTEIN BIOSENSORS | Board of Regents, The University of Texas System (US) | 2026-03-11 | — | — | EP | disclosed |
| US-20250290081-A1 | MICROORGANISMS FOR DITERPENE PRODUCTION | CARGILL, INCORPORATED | 2025-09-18 | — | — | US | disclosed |
| US-20250275914-A1 | PREPARATION METHOD AND CONTAINER FOR A TOPICAL WOUND HEALING GEL | REGENLAB USA LLC (US) | 2025-09-04 | — | — | US | disclosed |
| EP-0258290-A1 | METHOD AND ADDITIVES FOR IMPROVING THE QUALITY AND SHELF LIFE OF STORED BLOOD | VORA, Shobhana (US) | 1988-03-09 | — | — | EP | disclosed |
| WO-1987004072-A1 | METHOD AND ADDITIVES FOR IMPROVING THE QUALITY AND SHELF LIFE OF STORED BLOOD | VORA SHOBHANA (US) | 1987-07-16 | — | — | WO | disclosed |
| US-4451566-A | ENZYMATIC FERMENTATION OF SUGARS | SPENCER DONALD B | 1984-05-29 | — | — | US | disclosed |
| US-3929580-A | Creatine phosphokinase test indicator | "IL HOLDING S.P.A." | 1975-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250275914-A1 | PREPARATION METHOD AND CONTAINER FOR A TOPICAL WOUND HEALING GEL | BMX, PDGFA, PLAT | FGFR1 4040/4885PI4KA 4245/4885PI4K2B 4528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.