Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Adenine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 known ✓ | P11362 | 1/20 | 0.35 |
| ▸ | PI4KA | P42356 | 4/20 | 0.40 |
| ▸ | PI4K2B | Q8TCG2 | 4/20 | 0.40 |
| ▸ | PI4K2A | Q9BTU6 | 4/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.40 |
| ▸ | XDH | P47989 | 2/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PNP | P00491 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adenine SCHEMBL1035727 | 1.00 | PI4KA (0.40) | PI4KAPI4K2BPI4K2API4KBXDH | |
| Adenine SCHEMBL2411187 | 0.98 | PI4KA (0.39) | PI4KAPI4K2BPI4K2API4KBXDH | |
| Adenine SCHEMBL8509836 | 0.98 | PI4KA (0.39) | PI4KAPI4K2BPI4K2API4KBXDH | |
| Adenine SCHEMBL4908366 | 0.96 | PI4KA (0.38) | PI4KAPI4K2BPI4K2API4KBXDH | |
| Adenine SCHEMBL9275554 | 0.93 | PI4KA (0.38) | PI4KAPI4K2BPI4K2API4KBXDH | |
| Adenine SCHEMBL385841 | 0.88 | PI4KA (0.45) | PI4KAPI4K2BPI4K2API4KBXDH | |
| Adenine SCHEMBL8110 | 0.88 | PI4KA (0.48) | PI4KAPI4K2BPI4K2API4KBXDH | |
| Adenine SCHEMBL3414603 | 0.88 | PI4KA (0.48) | PI4KAPI4K2BPI4K2API4KBXDH | |
| Adenine SCHEMBL3416954 | 0.88 | PI4KA (0.48) | PI4KAPI4K2BPI4K2API4KBXDH | |
| Adenine SCHEMBL3413247 | 0.88 | PI4KA (0.48) | PI4KAPI4K2BPI4K2API4KBXDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 548 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4596713-A1 | DNA WITH ENHANCED RESISTANCE AGAINST EXONUCLEASES AND METHODS FOR THE PRODUCTION THEREOF | 4basebio UK Ltd (GB) | 2025-08-06 | — | — | EP | claimed |
| CN-119614709-A | Detection method and application of whole genome 5-hydroxymethylcytosine | 青岛科技大学 | 2025-03-14 | — | — | CN | claimed |
| WO-2024250923-A1 | CHEMICALLY MODIFIED NUCLEOSIDE, CHEMICALLY MODIFIED NUCLEOSIDE TRIPHOSPHATE AND USE THEREOF | 中国科学院深圳先进技术研究院 | 2024-12-12 | — | — | WO | claimed |
| US-20240350027-A1 | Methods and Apparatus for Benchtop Metabolite Profiling in Situ | VIBO HEALTH INC (US) | 2024-10-24 | — | — | US | claimed |
| EP-4436358-A1 | PROCESSES AND SYSTEMS FOR INCREASING DRY MATTER IN HYDROPONICALLY GROWN CELLULOSIC MATERIALS | Hydrogreen, Inc. (CA) | 2024-10-02 | — | — | EP | claimed |
| WO-2023096635-A1 | PROCESSES AND SYSTEMS FOR INCREASING DRY MATTER IN HYDROPONICALLY GROWN CELLULOSIC MATERIALS | HYDROGREEN, INC (CA) | 2023-06-01 | — | — | WO | claimed |
| US-20230157229-A1 | PROCESSES AND SYSTEMS FOR INCREASING DRY MATTER IN HYDROPONICALLY GROWN CELLULOSIC MATERIALS | Hydrogreen, Inc. (CA) | 2023-05-25 | — | — | US | claimed |
| CN-111505284-B | Test paper strip and sensor for detecting novel coronavirus SARS-CoV-2, and preparation and application thereof | 中国科学院重庆绿色智能技术研究院 | 2023-05-02 | — | — | CN | claimed |
| WO-2023022997-A1 | METHODS AND APPARATUS FOR BENCHTOP METABOLITE PROFILING IN SITU | ViBo Health Inc. (US) | 2023-02-23 | — | — | WO | claimed |
| US-20220275028-A1 | Systems, Methods And Compositions For Recombinant In Vitro Transcription And Translation Utilizing Thermophilic Proteins | NATURE'S TOOLBOX, INC. | 2022-09-01 | — | — | US | claimed |
| US-7022494-B2 | Detection of potassium ions using ion-sensitive enzymes | GENERAL ATOMICS (US) | 2006-04-04 | — | — | US | claimed |
| US-20050266508-A1 | Detection of potassium ions using ion-sensitive enzymes | DIAZYME LABORATORIES, INC. | 2005-12-01 | — | — | US | claimed |
| US-20050069970-A1 | Detection of potassium ions using ion-sensitive enzymes | GENERAL ATOMICS | 2005-03-31 | — | — | US | claimed |
| WO-2005029038-A2 | DETECTION OF POTASSIUM IONS USING ION-SENSITIVE ENZYMES | GENERAL ATOMICS (US) | 2005-03-31 | — | — | WO | claimed |
| US-20030212006-A1 | Method for reducing free radical formation in healthy individuals undergoing hypoxic exercise and medical conditions with increased oxygen free radicals | BIONERGY, INC. | 2003-11-13 | — | — | US | claimed |
| EP-1032700-A1 | SEPARATION OF NUCLEIC ACIDS BY ANTIBODIES TO HALOGENATED NUCLEOTIDES | New York Medical College (US) | 2000-09-06 | — | — | EP | claimed |
| CN-1049246-C | Method for preparing powder type culture-medium of animal cell | KANGDA AMINO ACID FASTORY SHAN (CN) | 2000-02-09 | — | — | CN | claimed |
| WO-1999006592-A9 | SEPARATION OF NUCLEIC ACIDS BY ANTIBODIES TO HALOGENATED NUCLEOTIDES | NEW YORK MEDICAL COLLEGE (US) | 1999-05-06 | — | — | WO | claimed |
| WO-1999006592-A1 | SEPARATION OF NUCLEIC ACIDS BY ANTIBODIES TO HALOGENATED NUCLEOTIDES | NEW YORK MEDICAL COLLEGE (US) | 1999-02-11 | — | — | WO | claimed |
| EP-0147713-A2 | Enzymatic ATP and FMN assay | Miles Italiana SpA (IT) | 1985-07-10 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220275028-A1 | Systems, Methods And Compositions For Recombinant In Vitro Transcription And Translation Utilizing Thermophilic Proteins | MRPL21, RNGTT, MRPS23 | FGFR1 3283/4885PI4KA 3291/4885PI4K2B 2668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.