Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | MMP8 | P22894 | 2/20 | 0.36 |
| ▸ | MMP13 | P45452 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.30 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11039656 | 0.78 | CA2 (0.37) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL11862620 | 0.78 | CA2 (0.38) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL8558677 | 0.75 | CA2 (0.41) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL9720142 | 0.75 | CA2 (0.39) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL7908262 | 0.75 | CA2 (0.39) | CA2CA1MMP1MMP2MMP9 | |
| Hydrochloric Acid SCHEMBL11788220 | 0.74 | CA2 (0.33) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL11337739 | 0.74 | CA2 (0.35) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL4809033 | 0.73 | MMP1 (0.39) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL5143705 | 0.72 | CA2 (0.43) | CA2CA1MMP1MMP2MMP9 | |
| Lithium Ion SCHEMBL31122764 | 0.72 | MMP1 (0.34) | CA2CA1MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0102240-B1 | METHOD FOR TREATING METALLIC OR CERAMIC SURFACES AT HIGH TEMPERATURES | TEIJIN LIMITED (JP) | 1990-10-31 | — | — | EP | disclosed |