Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14033171 | 0.96 | TDP1 (0.51) | TDP1L3MBTL1POLBKDM4ELMNA | |
| SCHEMBL10378725 | 0.82 | TDP1 (0.57) | TDP1MAPTKDM4ELMNARAB9A | |
| SCHEMBL10378810 | 0.82 | TDP1 (0.51) | TDP1L3MBTL1POLBMAPTKDM4E | |
| SCHEMBL30069487 | 0.77 | TDP1 (0.69) | TDP1L3MBTL1MAPTKDM4ELMNA | |
| SCHEMBL9046522 | 0.75 | ALDH1A1 (0.52) | TDP1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL14654334 | 0.74 | TDP1 (0.59) | TDP1L3MBTL1MAPTKDM4EALDH1A1 | |
| SCHEMBL13435255 | 0.74 | TDP1 (0.64) | TDP1L3MBTL1POLBKDM4ELMNA | |
| SCHEMBL14654314 | 0.73 | TDP1 (0.57) | TDP1L3MBTL1POLBMAPTKDM4E | |
| SCHEMBL9378271 | 0.73 | ALDH1A1 (0.45) | TDP1KDM4ERAB9AALDH1A1MEN1 | |
| SCHEMBL16855860 | 0.72 | TDP1 (0.56) | TDP1L3MBTL1MAPTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9097730-B2 | Fluorescein lactone ion indicators and their applications | AAT BIOQUEST, INC. (US) | 2015-08-04 | — | — | US | disclosed |
| US-8927224-B2 | Fluorescent ion indicators and their applications | AAT BIOQUEST, INC. (US) | 2015-01-06 | — | — | US | disclosed |
| US-8779165-B2 | Fluorescent ion indicators and their applications | AAT BIOQUEST, INC. (US) | 2014-07-15 | — | — | US | disclosed |
| US-20140080170-A1 | FLUORESCENT ION INDICATORS AND THEIR APPLICATIONS | AAT BIOQUEST, INC. (US) | 2014-03-20 | — | — | US | disclosed |
| US-20120183986-A1 | Fluorescent lactone ion indicators and their applications | AAT BIOQUEST, INC. | 2012-07-19 | — | — | US | disclosed |
| US-20110229924-A1 | Fluorescent ion indicators and their applications | ABD BIOQUEST, INC. | 2011-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110229924-A1 | Fluorescent ion indicators and their applications | SLC8B1, SLCO4C1, SLCO1A2 | TDP1 3602/4885L3MBTL1 3581/4885POLB 3981/4885 |
| US-20120183986-A1 | Fluorescent lactone ion indicators and their applications | CALR, FLI1, ECI1 | TDP1 4702/4885L3MBTL1 2465/4885POLB 4625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.