Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MLNR | O43193 | 12/20 | 0.42 |
| ▸ | GHSR | Q92847 | 7/20 | 0.42 |
| ▸ | DRD2 | P14416 | 4/20 | 0.42 |
| ▸ | DRD3 | P35462 | 4/20 | 0.42 |
| ▸ | HTR6 | P50406 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8570970 | 0.80 | KDM4E (0.43) | HTR2CMCHR1FAAHSMN1; SMN2ATM | |
| SCHEMBL10376300 | 0.75 | CYP2D6 (0.44) | CYP2D6ABCB1MLNRGHSRDRD2 | |
| SCHEMBL8569802 | 0.75 | MET (0.45) | SMN1; SMN2KCNH2 | |
| SCHEMBL10364825 | 0.74 | PLAU (0.41) | HTR2CMCHR1FAAHDRD2DRD3 | |
| Hydrochloric Acid SCHEMBL9732455 | 0.73 | KCNH2 (0.48) | CYP2D6HTR2CMCHR1FAAHCYP3A4 | |
| SCHEMBL10365458 | 0.72 | ALDH1A1 (0.46) | SMN1; SMN2CYP1A2CYP3A4CYP2C19GRIN1 | |
| SCHEMBL9716427 | 0.71 | MET (0.39) | CYP2D6MCHR1DRD2SMN1; SMN2CYP2C9 | |
| SCHEMBL10360469 | 0.71 | DRD2 (0.56) | CYP2D6HTR2CABCB1MLNRGHSR | |
| SCHEMBL2926846 | 0.69 | MCHR1 (0.65) | HTR2CMCHR1FAAHATM | |
| SCHEMBL9676242 | 0.69 | KCNH2 (0.51) | CYP2D6MCHR1DRD3SMN1; SMN2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0285323-B1 | ANTIARRHYTHMIC AGENTS | Pfizer Limited (GB) | 1990-11-28 | — | — | EP | claimed |
| EP-0285323-A1 | Antiarrhythmic agents | Pfizer Limited (GB) | 1988-10-05 | — | — | EP | claimed |
| EP-0285323-B1 | ANTIARRHYTHMIC AGENTS | Pfizer Limited (GB) | 1990-11-28 | — | — | EP | disclosed |
| US-4822793-A | Benzazepine antiarrhythmic agents | PFIZER INC. (US) | 1989-04-18 | — | — | US | disclosed |
| EP-0285323-A1 | Antiarrhythmic agents | Pfizer Limited (GB) | 1988-10-05 | — | — | EP | disclosed |