Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | PHGDH | O43175 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6354408 | 0.89 | — | — | |
| SCHEMBL285009 | 0.89 | ALDH1A1 (0.33) | HTTPOLBSMN1; SMN2 | |
| SCHEMBL303849 | 0.80 | CYP1A2 (0.52) | CYP1A2TDP1HTR1AHTTHSD11B1 | |
| SCHEMBL25924206 | 0.80 | ALDH1A1 (0.42) | HTTHSD11B1POLBLMNAGAA | |
| SCHEMBL8643734 | 0.80 | HSD11B1 (0.43) | TDP1HTTHSD11B1POLBSMN1; SMN2 | |
| SCHEMBL15932284 | 0.79 | HRH3 (0.35) | HTTPOLBSMN1; SMN2 | |
| SCHEMBL8646259 | 0.78 | ALDH1A1 (0.45) | HTTHSD11B1POLBLMNAGAA | |
| SCHEMBL10365770 | 0.78 | CYP1A2 (0.50) | CYP1A2TDP1HTR1AHTTHSD11B1 | |
| SCHEMBL8262866 | 0.76 | GAA (0.47) | POLBPHGDHMGLLLMNAGAA | |
| SCHEMBL4341361 | 0.75 | CA2 (0.43) | HSD11B1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160009733-A1 | REGULATION OF NITRIC OXIDE RELEASE AND BIOFILM DEVELOPMENT | UNIVERSITY OF WOLLONGONG (AU) | 2016-01-14 | — | — | US | disclosed |
| US-9156855-B2 | Regulation of nitric oxide release and biofilm development | Newsouth Innovation Pty Limited (AU) | 2015-10-13 | — | — | US | disclosed |
| US-20140221331-A1 | REGULATION OF NITRIC OXIDE RELEASE AND BIOFILM DEVELOPMENT | UNIVERSITY OF WOLLONGONG (AU) | 2014-08-07 | — | — | US | disclosed |
| EP-0104984-B1 | VINYLCARBAMIC ACID ESTERS AND THEIR PREPARATION | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1990-05-16 | — | — | EP | disclosed |
| US-4772695-A | DEHYDROHALOGENATION, INSECTICIDES | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1988-09-20 | — | — | US | disclosed |
| EP-0104984-A2 | Vinylcarbamic acid esters and their preparation | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1984-04-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160009733-A1 | REGULATION OF NITRIC OXIDE RELEASE AND BIOFILM DEVELOPMENT | NOS1, NOS2, NOS3 | CYP1A2 1447/4885TDP1 783/4885HTR1A 1395/4885 |
| US-20140221331-A1 | REGULATION OF NITRIC OXIDE RELEASE AND BIOFILM DEVELOPMENT | NOS1, NOS2, NOS3 | CYP1A2 1447/4885TDP1 783/4885HTR1A 1395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.