Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6963674 | 0.86 | POLB (0.55) | XDHSMN1; SMN2L3MBTL1NR4A3POLB | |
| SCHEMBL2870416 | 0.85 | PTPN1 (0.46) | XDHSMN1; SMN2L3MBTL1NR4A3POLB | |
| SCHEMBL10893230 | 0.85 | MAPK14 (0.53) | XDHSMN1; SMN2L3MBTL1NR4A3POLB | |
| SCHEMBL10890676 | 0.85 | RAB9A (0.49) | XDHSMN1; SMN2L3MBTL1NR4A3POLB | |
| SCHEMBL10892897 | 0.84 | XDH (0.43) | XDHSMN1; SMN2L3MBTL1NR4A3POLB | |
| SCHEMBL10833122 | 0.83 | ALDH1A1 (0.38) | XDHSMN1; SMN2L3MBTL1KEAP1NFE2L2 | |
| SCHEMBL10365343 | 0.83 | NPC1 (0.47) | XDHSMN1; SMN2POLBMAPK14MEN1 | |
| SCHEMBL10896747 | 0.83 | L3MBTL1 (0.44) | SMN1; SMN2L3MBTL1NR4A3POLBMAPT | |
| SCHEMBL10895563 | 0.82 | PTPN1 (0.54) | SMN1; SMN2MAPTMAPK14NPC1RAB9A | |
| SCHEMBL10340580 | 0.81 | ALDH1A1 (0.55) | SMN1; SMN2MAPTMEN1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4631343-A | Cyanopyrazole intermediates | ELI LILLY AND COMPANY (US) | 1986-12-23 | — | — | US | claimed |
| EP-0151867-B1 | CYANOPYRAZOLE HERBICIDES | ELI LILLY AND COMPANY (US) | 1990-01-10 | — | — | EP | disclosed |
| US-4631343-A | Cyanopyrazole intermediates | ELI LILLY AND COMPANY (US) | 1986-12-23 | — | — | US | disclosed |
| US-4589905-A | TERRESTRIAL AND AQUATIC APPLICATIONS | ELI LILLY AND COMPANY (US) | 1986-05-20 | — | — | US | disclosed |
| EP-0151867-A2 | Cyanopyrazole herbicides | ELI LILLY AND COMPANY (US) | 1985-08-21 | — | — | EP | disclosed |