Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.48 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10368553 | 0.90 | HPGD (0.52) | HPGDMAPK14NR4A3ALDH1A1NPC1 | |
| SCHEMBL10365971 | 0.83 | MAPK14 (0.50) | HPGDMAPK14NR4A3ALDH1A1NPC1 | |
| SCHEMBL10366594 | 0.82 | MEN1 (0.67) | HPGDMAPK14NR4A3ALDH1A1NPC1 | |
| SCHEMBL10367016 | 0.81 | NPC1 (0.54) | HPGDMAPK14NR4A3ALDH1A1NPC1 | |
| SCHEMBL10364979 | 0.81 | HPGD (0.53) | HPGDMAPK14NR4A3ALDH1A1NPC1 | |
| SCHEMBL10366595 | 0.80 | LMNA (0.46) | HPGDMAPK14NR4A3ALDH1A1NPC1 | |
| SCHEMBL10367397 | 0.80 | POLB (0.48) | HPGDALDH1A1NPC1RAB9AGAA | |
| SCHEMBL10366707 | 0.79 | POLB (0.52) | MAPK14NPC1RAB9APOLBMAPK11 | |
| SCHEMBL10366838 | 0.79 | RAB9A (0.49) | HPGDMAPK14ALDH1A1NPC1RAB9A | |
| SCHEMBL6963674 | 0.79 | POLB (0.55) | HPGDMAPK14NR4A3ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0151867-B1 | CYANOPYRAZOLE HERBICIDES | ELI LILLY AND COMPANY (US) | 1990-01-10 | — | — | EP | disclosed |
| US-4589905-A | TERRESTRIAL AND AQUATIC APPLICATIONS | ELI LILLY AND COMPANY (US) | 1986-05-20 | — | — | US | disclosed |
| EP-0151867-A2 | Cyanopyrazole herbicides | ELI LILLY AND COMPANY (US) | 1985-08-21 | — | — | EP | disclosed |