Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 20/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11257623 | 0.83 | HDAC3 (0.45) | — | |
| SCHEMBL11259485 | 0.79 | LTB4R (0.44) | TBXAS1 | |
| SCHEMBL11256211 | 0.77 | PPARG (0.42) | — | |
| SCHEMBL11268722 | 0.77 | GPBAR1 (0.47) | TBXAS1TBXA2R | |
| SCHEMBL11263458 | 0.76 | GPBAR1 (0.45) | — | |
| SCHEMBL11267185 | 0.76 | GPBAR1 (0.48) | TBXAS1TBXA2R | |
| SCHEMBL11255842 | 0.75 | ALDH1A1 (0.40) | — | |
| SCHEMBL11101135 | 0.72 | TBXAS1 (0.45) | TBXAS1TBXA2R | |
| SCHEMBL11263791 | 0.72 | GPBAR1 (0.48) | TBXAS1TBXA2R | |
| SCHEMBL3380708 | 0.72 | HDAC1 (0.70) | TBXAS1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129051-B1 | SUBSTITUTED INDOLES | CIBA-GEIGY AG (CH) | 1990-07-04 | — | — | EP | disclosed |
| EP-0129051-A2 | Substituted indoles | CIBA-GEIGY AG (CH) | 1984-12-27 | — | — | EP | disclosed |