Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 18/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7982484 | 0.76 | HTT (0.49) | HTT | |
| SCHEMBL7980326 | 0.75 | PTPN1 (0.44) | — | |
| SCHEMBL27738853 | 0.74 | CYP2A6 (0.39) | HTT | |
| SCHEMBL10374969 | 0.72 | TBXAS1 (0.51) | TBXAS1TBXA2R | |
| SCHEMBL7978811 | 0.72 | PTPN1 (0.46) | HTT | |
| SCHEMBL31518126 | 0.70 | AKR1B1 (0.47) | HTT | |
| SCHEMBL2193925 | 0.70 | GAA (0.44) | TBXAS1HTT | |
| SCHEMBL7985518 | 0.70 | LMNA (0.51) | HTT | |
| SCHEMBL16353627 | 0.69 | NOTUM (0.52) | TBXAS1TBXA2R | |
| SCHEMBL884611 | 0.68 | KCNA5 (0.69) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126401-A1 | Indole compounds | CIBA-GEIGY AG (CH) | 1984-11-28 | — | — | EP | disclosed |