Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 1/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | KDR | P35968 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10627 | 0.94 | EPHX2 (0.66) | EPHX2SMN1; SMN2MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL9505612 | 0.88 | THRB (0.63) | EPHX2SMN1; SMN2GAAMAPTL3MBTL1 | |
| SCHEMBL14006227 | 0.85 | EPHX2 (0.65) | EPHX2SMN1; SMN2MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL10638 | 0.83 | LMNA (0.67) | MAPTALDH1A1LMNATHRBKMT2A | |
| SCHEMBL11926736 | 0.82 | KDM4E (0.65) | EPHX2SMN1; SMN2GAAKDRALDH1A1 | |
| SCHEMBL4014247 | 0.81 | EPHX2 (0.79) | EPHX2MAPTRAB9AALDH1A1LMNA | |
| SCHEMBL4974321 | 0.81 | EPHX2 (0.70) | EPHX2SMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL863522 | 0.79 | SMN1; SMN2 (0.81) | SMN1; SMN2GAAMAPTALDH1A1LMNA | |
| SCHEMBL1801810 | 0.77 | CD274 (0.62) | EPHX2SMN1; SMN2GAAKDRALDH1A1 | |
| SCHEMBL10132797 | 0.77 | EPHX2 (0.67) | EPHX2MAPTNPC1RAB9AKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488489-A2 | C-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | Pfizer Inc. (US) | 2012-08-22 | — | — | EP | disclosed |
| WO-2011045703-A2 | C-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 2011-04-21 | — | — | WO | disclosed |