Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 7/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.64 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.64 |
| ▸ | HTR2A | P28223 | 1/20 | 0.64 |
| ▸ | SCN1A | P35498 | 1/20 | 0.64 |
| ▸ | HTR2B | P41595 | 1/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.64 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.64 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.64 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.64 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9505612 | 0.93 | THRB (0.63) | EPHX2MAPK1ALDH1A1CYP1A2CHRM2 | |
| SCHEMBL14006223 | 0.90 | LMNA (0.68) | ALDH1A1CYP1A2CHRM2HTR2AKCNH2 | |
| SCHEMBL10627 | 0.89 | EPHX2 (0.66) | EPHX2MAPK1ALDH1A1CYP1A2CHRM2 | |
| SCHEMBL14006202 | 0.88 | LMNA (0.70) | EPHX2ALDH1A1CYP1A2CHRM2HTR2A | |
| SCHEMBL14006288 | 0.88 | LMNA (0.70) | EPHX2ALDH1A1CYP1A2CHRM2HTR2A | |
| SCHEMBL14006284 | 0.88 | EPHX2 (0.60) | EPHX2ALDH1A1MAPTL3MBTL1LMNA | |
| SCHEMBL14006285 | 0.85 | EPHX2 (0.62) | EPHX2ALDH1A1MAPTL3MBTL1LMNA | |
| SCHEMBL10378 | 0.85 | LIPE (0.58) | EPHX2ALDH1A1MAPTL3MBTL1LMNA | |
| SCHEMBL14006291 | 0.82 | EPHX2 (0.58) | EPHX2ALDH1A1KCNH2MAPTL3MBTL1 | |
| SCHEMBL4369662 | 0.81 | ALDH1A1 (0.63) | EPHX2MAPK1ALDH1A1CYP1A2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080275028-A1 | Modulators or Alpha7 Nicotinic Acetylcholine Receptors and Therapeutic Uses Thereof | SIENA BIOTECH S.P.A. (IT) | 2008-11-06 | — | — | US | disclosed |
| US-20080275028-A1 | Modulators or Alpha7 Nicotinic Acetylcholine Receptors and Therapeutic Uses Thereof | SIENA BIOTECH S.P.A. (IT) | 2008-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080275028-A1 | Modulators or Alpha7 Nicotinic Acetylcholine Receptors and Therapeutic Uses Thereof | CHRNA7, CHRNA5, CHRNA1 | EPHX2 777/4885MAPK1 1753/4885ALDH1A1 2091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.