Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 10/20 | 0.66 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.62 |
| ▸ | HTR2A | P28223 | 1/20 | 0.62 |
| ▸ | SCN1A | P35498 | 1/20 | 0.62 |
| ▸ | HTR2B | P41595 | 1/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.62 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.62 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10378 | 0.94 | LIPE (0.58) | EPHX2ALDH1A1LMNAMAPTL3MBTL1 | |
| SCHEMBL10638 | 0.89 | LMNA (0.67) | HRH3ALDH1A1CYP1A2CHRM2HTR2A | |
| SCHEMBL14006227 | 0.89 | EPHX2 (0.65) | EPHX2HRH3MAPK1ALDH1A1CYP1A2 | |
| SCHEMBL9505612 | 0.85 | THRB (0.63) | EPHX2HRH3MAPK1ALDH1A1CYP1A2 | |
| SCHEMBL4261838 | 0.79 | EPHX2 (1.00) | EPHX2ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL14006223 | 0.78 | LMNA (0.68) | HRH3ALDH1A1CYP1A2CHRM2HTR2A | |
| SCHEMBL4256144 | 0.78 | EPHX2 (1.00) | EPHX2 | |
| SCHEMBL9390735 | 0.78 | L3MBTL1 (0.74) | ALDH1A1CYP1A2MAPTL3MBTL1SMN1; SMN2 | |
| Pramoxine SCHEMBL26020 | 0.78 | ALDH1A1 (1.00) | HRH3MAPK1ALDH1A1CYP1A2CHRM2 | |
| SCHEMBL13949485 | 0.78 | EPHX2 (0.67) | EPHX2HRH3MAPK1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488489-A2 | C-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | Pfizer Inc. (US) | 2012-08-22 | — | — | EP | disclosed |
| WO-2011045703-A2 | C-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 2011-04-21 | — | — | WO | disclosed |