SCHEMBL103816

SCHEMBL103816

Brc1ccc2ccoc2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 5/20 0.44
KDM4E B2RXH2 2/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44
NFKB1 P19838 1/20 0.44
MAOA P21397 1/20 0.44
ACHE P22303 1/20 0.44
CYP2C19 P33261 1/20 0.44
HSD17B10 Q99714 1/20 0.44
HTR1B P28222 5/20 0.41
MEN1 O00255 1/20 0.38
ALDH1A1 P00352 1/20 0.38
MAPT P10636 1/20 0.38
KMT2A Q03164 1/20 0.38
CHRM2 P08172 2/20 0.37
CHRM1 P11229 2/20 0.37
CHRM3 P20309 2/20 0.37
IDO1 P14902 1/20 0.36
AHR P35869 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9581238 0.98 CYP2A6 (0.42) CYP2A6KDM4ECYP3A4CYP2D6CYP2C9
Formic Acid SCHEMBL28208544 0.88 CYP2A6 (0.42) CYP2A6KDM4ECYP3A4CYP2D6CYP2C9
SCHEMBL28318294 0.83 DYRK1A (0.46) CYP2A6KDM4ECYP3A4CYP2D6CYP2C9
SCHEMBL6733 0.81 CYP2A6 (0.50) CYP2A6KDM4ECYP3A4CYP2D6CYP2C9
SCHEMBL28844051 0.80 MAOB (0.45) KDM4EMAOAHSD17B10MEN1ALDH1A1
Ethoxycarbonyl Group SCHEMBL28245391 0.79 CHRM2 (0.41) CYP2A6KDM4ECYP3A4CYP2D6CYP2C9
Formaldehyde SCHEMBL28085404 0.76 CYP2A6 (0.50) CYP2A6KDM4ECYP3A4CYP2D6CYP2C9
SCHEMBL29756248 0.75 DYRK1A (0.50) CYP2A6KDM4ECYP3A4CYP2D6CYP2C9
SCHEMBL2149910 0.73 CYP2A6 (0.54) CYP2A6KDM4ECYP3A4CYP2D6CYP2C9
SCHEMBL29329001 0.73 CYP2A6 (0.45) CYP2A6KDM4ECYP3A4CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 311 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113122061-A Quantum dot ink and preparation method of quantum dot film TCL集团股份有限公司 2021-07-16 CN claimed
CN-108129430-A A kind of synthetic method of Li Tasite intermediates 重庆圣华曦药业股份有限公司 2018-06-08 CN claimed
US-12613246-B2 Fluorescent probe and protein labeling method FLUORESCENCE DIAGNOSIS (SHANGHAI) BIOTECH COMPANY LTD. (CN) 2026-04-28 US disclosed
US-12404257-B2 Advantageous benzofuran compositions for mental disorders or enhancement TACTOGEN INC (US) 2025-09-02 US disclosed
US-12365661-B2 Advantageous benzofuran compositions for mental disorders or enhancement TACTOGEN INC (US) 2025-07-22 US disclosed
US-20250221979-A1 NOVEL HETEROCYCLIC COMPOUND SHOUYAO HOLDINGS BEIJING CO LTD (CN) 2025-07-10 US disclosed
US-12344591-B2 Advantageous benzofuran compositions for mental disorders or enhancement TACTOGEN INC (US) 2025-07-01 US disclosed
US-20250186433-A1 ACSS2 INHIBITORS AND METHODS OF USE THEREOF EPIVARIO, INC. 2025-06-12 US disclosed
US-20250188049-A1 ADVANTAGEOUS BENZOFURAN COMPOSITIONS FOR MENTAL DISORDERS OR ENHANCEMENT TACTOGEN INC (US) 2025-06-12 US disclosed
EP-3647315-B9 PHOSPHORUS-CONTAINING COMPOUND AND PREPARATION AND USE THEREOF VIVAVISION BIOTECH LTD (CN) 2025-06-04 EP disclosed
CN-120040398-A Advantageous benzofuran compositions for mental disorders or mental enhancement 泰科根公司 2025-05-27 CN disclosed
EP-0355827-B1 Hydantoin derivatives MOCHIDA PHARM CO LTD (JP) 1997-01-02 EP disclosed
US-RE35279-E ALDOSE REDUCTASE INHIBITORS MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1996-06-18 US disclosed
EP-0693475-A1 1-Phenyl-3-dimethylamino-propane derivatives having pharmacological activity Grünenthal GmbH (DE) 1996-01-24 EP disclosed
EP-0560554-A2 Antitumor compositions and methods of treatment ELI LILLY AND COMPANY (US) 1993-09-15 EP disclosed
US-5202339-A Hypoglycemic, hypolipedemic agents MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1993-04-13 US disclosed
US-5169860-A Benzofuran or benzothiophene arylsulfonylureas ELI LILLY AND COMPANY (US) 1992-12-08 US disclosed
US-5004751-A Antidiabetic agents; aldoe reductase inhibitors MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1991-04-02 US disclosed
WO-1990002126-A1 HYDANTOIN DERIVATIVES MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1990-03-08 WO disclosed
EP-0355827-A2 Hydantoin derivatives MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1990-02-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250186433-A1 ACSS2 INHIBITORS AND METHODS OF USE THEREOF ACSS2, GLS2, ADSS2 CYP2A6 3751/4885KDM4E 2609/4885CYP3A4 3671/4885
US-12404257-B2 Advantageous benzofuran compositions for mental disorders or enhancement BDNF, CREBBP, ELF3 CYP2A6 884/4885KDM4E 1815/4885CYP3A4 1609/4885
US-12613246-B2 Fluorescent probe and protein labeling method CYFIP1, IK, CYFIP2 CYP2A6 4348/4885KDM4E 4624/4885CYP3A4 4487/4885
US-12344591-B2 Advantageous benzofuran compositions for mental disorders or enhancement BDNF, CREBBP, ELF3 CYP2A6 884/4885KDM4E 1815/4885CYP3A4 1609/4885
US-20250221979-A1 NOVEL HETEROCYCLIC COMPOUND MAPT, MNAT1, MAT2A CYP2A6 704/4885KDM4E 3698/4885CYP3A4 1605/4885
US-12365661-B2 Advantageous benzofuran compositions for mental disorders or enhancement BDNF, CREBBP, ELF3 CYP2A6 884/4885KDM4E 1815/4885CYP3A4 1609/4885
US-20250188049-A1 ADVANTAGEOUS BENZOFURAN COMPOSITIONS FOR MENTAL DISORDERS OR ENHANCEMENT BDNF, CREBBP, ELF3 CYP2A6 884/4885KDM4E 1815/4885CYP3A4 1609/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.