SCHEMBL6733

SCHEMBL6733

Brc1ccc2occc2c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 5/20 0.50
DYRK1A Q13627 5/20 0.47
IDO1 P14902 2/20 0.46
CDK9 P50750 1/20 0.46
PIM1 P11309 1/20 0.41
AHR P35869 1/20 0.41
HTR1B P28222 2/20 0.41
EPM2A O95278 1/20 0.41
PTPRC P08575 1/20 0.41
PTPN6 P29350 1/20 0.41
CDC14A Q9UNH5 1/20 0.41
PTPN22 Q9Y2R2 1/20 0.41
GPR183 P32249 1/20 0.40
CTNNB1 P35222 1/20 0.40
WNT3A P56704 1/20 0.40
KDM4E B2RXH2 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
NFKB1 P19838 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formaldehyde SCHEMBL28085404 0.94 CYP2A6 (0.50) CYP2A6DYRK1AIDO1CDK9PIM1
Acetaldehyde SCHEMBL4860532 0.88 CYP2A6 (0.55) CYP2A6DYRK1AIDO1CDK9PIM1
SCHEMBL27741085 0.83 DYRK1A (0.65) CYP2A6DYRK1ACDK9
Trifluoromethanesulfonic Acid SCHEMBL28759270 0.81 EPM2A (0.47) CYP2A6IDO1PIM1HTR1BEPM2A
SCHEMBL15544212 0.81 DYRK1A (0.40) CYP2A6DYRK1AIDO1HTR1BCTNNB1
SCHEMBL103816 0.81 CYP2A6 (0.44) CYP2A6IDO1AHRHTR1BKDM4E
SCHEMBL20180505 0.80 DYRK1A (0.56) DYRK1AIDO1CDK9MAOA
SCHEMBL9581238 0.79 CYP2A6 (0.42) CYP2A6IDO1AHRHTR1BKDM4E
SCHEMBL7406922 0.77 DYRK1A (0.46) DYRK1ACDK9
SCHEMBL4029853 0.77 MAOA (0.41) CYP2A6PIM1AHRKDM4ENFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 628 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114573534-B Preparation method of 5-bromobenzofuranone 八叶草健康产业研究院(厦门)有限公司 2025-01-24 CN claimed
CN-116120374-A Phosphine ligand catalyst, preparation method thereof and application thereof in synthesizing p-hydroxyanisole 万华化学集团股份有限公司 2023-05-16 CN claimed
CN-115477631-A Synthesis method of compound containing dimethyl enol group 大理大学 2022-12-16 CN claimed
CN-114957312-A Aryl silicon compound of conjugated olefin and preparation method and application thereof 南京工业大学 2022-08-30 CN claimed
CN-114853795-A Arylboron compound of conjugated olefin and preparation method and application thereof 南京工业大学 2022-08-05 CN claimed
CN-114685251-A Direct cross-coupling reaction method of diaryl sulfoxide and aryl bromide 南京工业大学 2022-07-01 CN claimed
CN-113402350-A Biaryl compound and preparation method and application thereof 南京工业大学 2021-09-17 CN claimed
CN-107266413-A Heterocycle and phenylpropionic acid derivative and its preparation method and application 上海大学 2017-10-20 CN claimed
CN-103724304-B The preparation method of 5-bromobenzofuran 定陶县友帮化工有限公司 2016-08-17 CN claimed
US-20260092034-A1 7-AZAINDOLE ANALOGS AND METHODS OF TREATING NEUROLOGICAL DISORDERS USING THE SAME KULEON LLC (US) 2026-04-02 US disclosed
US-20260085064-A1 SUBSTITUTED BENZOFURANYL AND BENZOXAZOLYL COMPOUNDS AND USES THEREOF KARYOPHARM THERAPEUTICS INC (US) 2026-03-26 US disclosed
EP-4131456-B1 ORGANIC LIGHT-EMITTING DEVICE SFC CO LTD (KR) 2026-02-18 EP disclosed
US-12543493-B2 Organic light-emitting device SFC CO., LTD. (KR) 2026-02-03 US disclosed
US-20250388570-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME SFC CO., LTD (KR) 2025-12-25 US disclosed
US-4341792-A ANTIDIABETIC AND CARDIOTONIC AGENTS PFIZER INC. (US) 1982-07-27 US disclosed
EP-0026593-A1 Bicyclic keto- and amino- acids, esters and amides and pharmaceutical compositions thereof Pfizer Limited (GB) 1981-04-08 EP disclosed
US-4024273-A Coronary vasodilator and anti-anginal compositions comprising substituted benzofurans and benzothiophenes and methods of producing coronary vasodilation and anti-anginal activity SMITHKLINE CORPORATION (US) 1977-05-17 US disclosed
US-3983245-A CORONARY VASODILATORS SMITHKLINE CORPORATION (US) 1976-09-28 US disclosed
US-3975537-A SUBSTITUTED BENZOFURANS SMITH KLINE (US) 1976-08-17 US disclosed
US-3947470-A CORONARY VASODILATORS, TREATMENT OF ANGINA PECTORIS SMITHKLINE CORPORATION (US) 1976-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092034-A1 7-AZAINDOLE ANALOGS AND METHODS OF TREATING NEUROLOGICAL DISORDERS USING THE SAME HTR2C, HTR7, HTR6 CYP2A6 242/4885DYRK1A 1423/4885IDO1 366/4885
US-12543493-B2 Organic light-emitting device CRY1, CRY2, AOC2 CYP2A6 689/4885DYRK1A 3355/4885IDO1 502/4885
US-20250388570-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME AOC2, TRPC1, VDAC1 CYP2A6 3007/4885DYRK1A 3865/4885IDO1 1205/4885
US-20260085064-A1 SUBSTITUTED BENZOFURANYL AND BENZOXAZOLYL COMPOUNDS AND USES THEREOF BCL6, MALT1, BCL6B CYP2A6 208/4885DYRK1A 4723/4885IDO1 1416/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.