Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9465134 | 0.87 | PTGS2 (0.52) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| SCHEMBL9465136 | 0.87 | PTGS2 (0.52) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| SCHEMBL9407718 | 0.86 | ALDH1A1 (0.57) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| SCHEMBL1008123 | 0.85 | ALDH1A1 (0.56) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| SCHEMBL1008121 | 0.85 | ALDH1A1 (0.56) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| SCHEMBL1007459 | 0.83 | ALDH1A1 (0.53) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| SCHEMBL1007460 | 0.83 | ALDH1A1 (0.53) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| SCHEMBL29260522 | 0.81 | PTGS2 (0.55) | ALDH1A1CYP3A4TSHRPTGS2MAOB | |
| SCHEMBL9464294 | 0.81 | TBXAS1 (0.55) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| SCHEMBL9464872 | 0.81 | TBXAS1 (0.55) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4933365-A | ANTIFLAMMATORY AGENTS, ANTIALLERGENS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1990-06-12 | — | — | US | disclosed |