SCHEMBL29260522

SCHEMBL29260522

COC(=O)CCC/C=C/c1ccc(Cl)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.55
CYP1A2 P05177 2/20 0.47
MAPT P10636 2/20 0.47
CYP4F2 P78329 1/20 0.44
CYP4A11 Q02928 1/20 0.44
TSHR P16473 2/20 0.42
TP53 P04637 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
PKM P14618 1/20 0.42
NFKB1 P19838 1/20 0.42
MAPK1 P28482 1/20 0.42
CYP2C19 P33261 1/20 0.42
THPO P40225 1/20 0.42
MEN1 O00255 1/20 0.42
NPC1 O15118 1/20 0.42
GMNN O75496 1/20 0.42
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42
RAB9A P51151 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9465136 0.94 PTGS2 (0.52) PTGS2CYP1A2MAPTCYP4F2CYP4A11
SCHEMBL9465134 0.94 PTGS2 (0.52) PTGS2CYP1A2MAPTCYP4F2CYP4A11
SCHEMBL10904338 0.85 PTGS2 (0.47) PTGS2CYP1A2MAPTTSHRTP53
SCHEMBL9427239 0.85 GSK3B (0.55) CYP1A2MAPTCYP3A4CYP2C19NPC1
SCHEMBL9427247 0.85 GSK3B (0.55) CYP1A2MAPTCYP3A4CYP2C19NPC1
SCHEMBL9208139 0.85 GSK3B (0.55) CYP1A2MAPTCYP3A4CYP2C19NPC1
SCHEMBL10653530 0.84 AKT1 (0.51) CYP4F2CYP4A11TSHRLMNAMAOB
SCHEMBL29016750 0.84 AKT1 (0.51) CYP4F2CYP4A11TSHRLMNAMAOB
SCHEMBL10384261 0.81 ALDH1A1 (0.57) PTGS2MAPTCYP4F2CYP4A11TSHR
SCHEMBL10505231 0.81 TBXAS1 (0.50) CYP1A2MAPTTP53CYP3A4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118206514-A Reaction method for preparing olefin by deacylation of visible light induced ketone 国科大杭州高等研究院 2024-06-18 CN disclosed