Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TGM2 | P21980 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28980360 | 0.89 | CYP3A4 (0.57) | IDO1EPHX2DHODHALDH1A1TRPV1 | |
| SCHEMBL28392252 | 0.78 | NPC1 (0.66) | EPHX2ALDH1A1TRPV1NPC1RAB9A | |
| SCHEMBL20984340 | 0.77 | EPHX2 (0.59) | IDO1EPHX2DHODHTRPV1KIF11 | |
| SCHEMBL669442 | 0.77 | EPHX2 (0.70) | IDO1EPHX2DHODHALDH1A1TRPV1 | |
| SCHEMBL1978109 | 0.76 | EPHX2 (0.57) | EPHX2DHODHALDH1A1TRPV1KIF11 | |
| SCHEMBL10384358 | 0.74 | TSHR (0.52) | IDO1EPHX2ALDH1A1SMN1; SMN2NPC1 | |
| Nitrogen SCHEMBL28799837 | 0.74 | SMN1; SMN2 (0.66) | IDO1EPHX2DHODHALDH1A1TRPV1 | |
| SCHEMBL9302776 | 0.74 | KIF11 (0.61) | EPHX2ALDH1A1TRPV1KIF11TGM2 | |
| SCHEMBL28191918 | 0.74 | GAA (0.62) | IDO1EPHX2DHODHALDH1A1TRPV1 | |
| SCHEMBL23367251 | 0.71 | TGM2 (0.53) | EPHX2ALDH1A1TRPV1KIF11TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4916149-A | Diuretic and saluretic 4-chloro-3-sulfamoylbenzoic acid hydrazides | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1990-04-10 | — | — | US | disclosed |