Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TCF4 | P15884 | 1/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.37 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10385011 | 1.00 | NQO2 (0.43) | NQO2ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL10612472 | 0.81 | NQO2 (0.49) | NQO2ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL9726963 | 0.78 | TCF4 (0.46) | NQO2ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL4683697 | 0.76 | ALDH1A1 (0.49) | ALDH1A1KDM4EMAPTHPGDERCC5 | |
| SCHEMBL9799379 | 0.74 | SMN1; SMN2 (0.37) | ALDH1A1HPGDRAB9ASMN1; SMN2TDP1 | |
| SCHEMBL9799375 | 0.74 | SMN1; SMN2 (0.37) | ALDH1A1HPGDRAB9ASMN1; SMN2TDP1 | |
| SCHEMBL10425548 | 0.73 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPTERCC5FEN1 | |
| SCHEMBL9726725 | 0.72 | HMGCR (0.43) | ALDH1A1KDM4EMAPTTCF4CTNNB1 | |
| SCHEMBL9726718 | 0.72 | HMGCR (0.43) | ALDH1A1KDM4EMAPTTCF4CTNNB1 | |
| SCHEMBL9727011 | 0.72 | ALDH1A1 (0.51) | NQO2ALDH1A1KDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4939265-A | Intermediates and process for the preparation of antihypercholesterolemic tetrazole compounds | BRISTOL-MYERS COMPANY (US) | 1990-07-03 | — | — | US | disclosed |
| US-4898949-A | Intermediates for the preparation of antihypercholesterolemic tetrazole compounds | BRISTOL-MYERS COMPANY (US) | 1990-02-06 | — | — | US | disclosed |