Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 6/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3125917 | 0.87 | KDM4E (0.56) | LMNAMEN1KMT2ACYP3A4MAPT | |
| Hydrochloric Acid SCHEMBL10385497 | 0.85 | KDM4E (0.55) | LMNAMEN1KMT2ACYP3A4MAPT | |
| SCHEMBL7910478 | 0.77 | ALDH1A1 (0.44) | LMNAKMT2AKDM4ESLC6A3TSHR | |
| SCHEMBL5074488 | 0.76 | CA1 (0.42) | LMNAMAPTTSHRTP53ALDH1A1 | |
| SCHEMBL5827955 | 0.76 | LMNA (0.62) | LMNAMEN1KMT2ACYP3A4MAPT | |
| SCHEMBL7366543 | 0.75 | LMNA (0.69) | LMNAMEN1KMT2ACYP3A4MAPT | |
| SCHEMBL7635112 | 0.74 | RAB9A (0.35) | LMNAMEN1KMT2ACYP3A4MAPT | |
| SCHEMBL9626775 | 0.74 | LMNA (0.72) | LMNAMEN1KMT2ACYP3A4MAPT | |
| SCHEMBL18304615 | 0.74 | ENPP2 (0.46) | LMNAMEN1KMT2ACYP3A4MAPT | |
| SCHEMBL8982612 | 0.74 | LMNA (0.72) | LMNAMEN1KMT2ACYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4927928-A | SKIN DISORDERS, EYES, ANTITUMOR | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES C.I.R.D. (FR) | 1990-05-22 | — | — | US | disclosed |