Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1180898 | 0.81 | PRNP (0.34) | HSD11B1NPC1RAB9AALDH1A1 | |
| SCHEMBL7574870 | 0.79 | ALDH1A1 (0.39) | NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL3063032 | 0.77 | KDM4E (0.35) | THRBSMN1; SMN2ALDH1A1 | |
| SCHEMBL3956163 | 0.72 | CA1 (0.42) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL27766424 | 0.72 | GABRA1 (0.39) | SMN1; SMN2 | |
| SCHEMBL5175506 | 0.72 | KDM4E (0.39) | NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8364149 | 0.71 | CA5A (0.32) | THRB | |
| SCHEMBL6975365 | 0.71 | KDM4E (0.34) | THRBNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL27855180 | 0.71 | MAOA (0.38) | ALDH1A1 | |
| SCHEMBL9870004 | 0.69 | TDP1 (0.42) | THRBSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1022632-C | Carboxamide compounds, process for preparing same and pharmaceutical composition containing same | OTSUKA PHARMA CO LTD (JP) | 1993-11-03 | — | — | CN | disclosed |
| US-4971957-A | ANTILIPEMIC AGENTS, ANTICHOLESTEROL AGENTS, BENZENECARBOXAMIDOPHOSPHONATES OR BENZENETHIOCARBOXAMIDOPHOSPHONATES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1990-11-20 | — | — | US | disclosed |
| CN-1040029-A | Carboxylic acid amide compounds and preparation method thereof and contain the pharmaceutical composition of this carboxylic acid amine compound | OTSUKA PHARMA CO LTD (JP) | 1990-02-28 | — | — | CN | disclosed |