Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.56 |
| ▸ | TUBB | P07437 | 1/20 | 0.56 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.56 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.56 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.56 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.56 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.56 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.56 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.56 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.56 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.56 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.56 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.56 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.56 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9198420 | 0.88 | MAPT (0.69) | MAPTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL28446243 | 0.86 | CA2 (0.65) | MAPTKDM4ELOXL2LMNACA1 | |
| SCHEMBL10397856 | 0.85 | MAPT (0.66) | MAPTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL10396473 | 0.85 | MAPT (0.59) | MAPTKDM4ELOXL2LMNACA1 | |
| SCHEMBL6070478 | 0.84 | TUBB4A (0.56) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10397052 | 0.84 | MAPT (0.64) | MAPTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL69454 | 0.83 | LOXL2 (0.70) | MAPTKDM4ELOXL2CA1CA2 | |
| SCHEMBL10395972 | 0.81 | MAPT (0.64) | MAPTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL10396475 | 0.79 | MAPT (0.69) | MAPTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8993003 | 0.78 | CA1 (0.78) | MAPTKDM4ELOXL2LMNACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4910206-A | Endotoxin induced lung injury | SANDOZ PHARMACEUTICALS CORP. (US) | 1990-03-20 | — | — | US | disclosed |