SCHEMBL10397136

SCHEMBL10397136

CCc1cccc(C(=O)c2ccccc2)c1N

nearest known ligand 0.73

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ABCB11 O95342 1/20 0.57
LMNA P02545 1/20 0.57
PTGS1 P23219 1/20 0.57
ADORA1 P30542 1/20 0.57
PTGS2 P35354 1/20 0.57
GAA P10253 1/20 0.55
MAPT P10636 1/20 0.55
AKR1C3 P42330 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31707350 1.00 ABCB11 (0.57) ABCB11LMNAPTGS1ADORA1PTGS2
SCHEMBL30549386 0.86 MAPT (0.50) LMNAPTGS1PTGS2GAAMAPT
SCHEMBL16979055 0.86 ABCB11 (0.57) ABCB11LMNAPTGS1ADORA1PTGS2
SCHEMBL27722742 0.86 ABCB11 (0.51) ABCB11LMNAPTGS1ADORA1PTGS2
SCHEMBL13241358 0.85 ABCB11 (0.74) ABCB11LMNAPTGS1ADORA1PTGS2
SCHEMBL9999972 0.85 ABCB11 (0.61) ABCB11LMNAPTGS1ADORA1PTGS2
SCHEMBL3002445 0.85 CES2 (0.47) ABCB11LMNAPTGS1ADORA1PTGS2
SCHEMBL4459472 0.85 ABCB11 (0.56) ABCB11LMNAPTGS1ADORA1PTGS2
Amfenac SCHEMBL30777846 0.85 ABCB11 (0.78) ABCB11LMNAPTGS1ADORA1PTGS2
Amfenac SCHEMBL24249 0.85 ABCB11 (0.78) ABCB11LMNAPTGS1ADORA1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109673-A1 ACETYL-COA CARBOXYLASE MODULATORS MONSANTO TECHNOLOGY LLC (US) 2026-04-23 US disclosed
US-12448355-B2 Acetyl-CoA carboxylase modulators MONSANTO TECHNOLOGY LLC (US) 2025-10-21 US disclosed
WO-2022199625-A1 PHOTOSENSITIVE RESIN COMPOSITION HAVING IMPROVED SYSTEM HUE STABILITY 常州正洁智造科技有限公司 2022-09-29 WO disclosed
US-20210246106-A1 ACETYL-COA CARBOXYLASE MODULATORS MONSANTO TECHNOLOGY LLC (US) 2021-08-12 US disclosed
WO-2021104224-A1 EO/PO-MODIFIED 9-PHENYLACRIDINE PHOTOSENSITIZER AND APPLICATION THEREOF 常州强力电子新材料股份有限公司 2021-06-03 WO disclosed
US-10995070-B2 Acetyl-CoA carboxylase modulators MONSANTO TECHNOLOGY LLC (US) 2021-05-04 US disclosed
WO-2020233700-A1 HABI PHOTOINITIATOR CAPABLE OF IMPROVING SYSTEM STABILITY AND APPLICATION THEREOF 常州格林感光新材料有限公司 (CN) 2020-11-26 WO disclosed
WO-2020200020-A1 HEXAARYLBIIMIDAZOLE PHOTOINITIATOR AND APPLICATION THEREOF 常州格林感光新材料有限公司 2020-10-08 WO disclosed
CN-104749882-B Coloring composition, colored cured film, and display element JSR株式会社 2020-01-31 CN disclosed
US-20190135757-A1 ACETYL-COA CARBOXYLASE MODULATORS MONSANTO TECHNOLOGY LLC (US) 2019-05-09 US disclosed
CN-103906735-A Novel aryl-quinoline derivatives HOFFMANN LA ROCHE 2014-07-02 CN disclosed
US-8461263-B2 End-modified diene copolymer having good compatibility with reinforcing silica and preparation method thereof KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2013-06-11 US disclosed
WO-2013064465-A1 NEW ARYL-QUINOLINE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2013-05-10 WO disclosed
WO-2013064465-A1 NEW ARYL-QUINOLINE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2013-05-10 WO disclosed
US-20130116234-A1 ARYL-QUINOLINE DERIVATIVES HOFFMANN-LA ROCHE INC. (US) 2013-05-09 US disclosed
US-20130116234-A1 ARYL-QUINOLINE DERIVATIVES HOFFMANN-LA ROCHE INC. (US) 2013-05-09 US disclosed
US-20130116234-A1 ARYL-QUINOLINE DERIVATIVES HOFFMANN-LA ROCHE INC. (US) 2013-05-09 US disclosed
US-20130090427-A1 END-MODIFIED DIENE COPOLYMER HAVING GOOD COMPATIBILITY WITH REINFORCING SILICA AND PREPARATION METHOD THEREOF KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2013-04-11 US disclosed
US-4898874-A Acetic acid derivatives of 3-aryl-2,1-benzisoxazole and esters and amides thereof A. H. ROBINS COMPANY, INC. (US) 1990-02-06 US disclosed
EP-0260924-A1 Antiinflammatory derivatives of 3-aryl-2,1-benzisoxazole A.H. ROBINS COMPANY, INCORPORATED (US) 1988-03-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210246106-A1 ACETYL-COA CARBOXYLASE MODULATORS ACACA, ACACB, ACAT2 ABCB11 4157/4885LMNA 4101/4885PTGS1 2570/4885
US-12448355-B2 Acetyl-CoA carboxylase modulators ACACA, ACACB, ACAT2 ABCB11 4157/4885LMNA 4101/4885PTGS1 2570/4885
US-20130116234-A1 ARYL-QUINOLINE DERIVATIVES FABP1, FABP4, FABP5 ABCB11 1826/4885LMNA 1769/4885PTGS1 2518/4885
US-20190135757-A1 ACETYL-COA CARBOXYLASE MODULATORS ACACA, ACACB, ACAT2 ABCB11 4157/4885LMNA 4101/4885PTGS1 2570/4885
US-10995070-B2 Acetyl-CoA carboxylase modulators ACACA, ACACB, ACAT2 ABCB11 4157/4885LMNA 4101/4885PTGS1 2570/4885
US-20260109673-A1 ACETYL-COA CARBOXYLASE MODULATORS ACACA, ACACB, HACL2 ABCB11 1464/4885LMNA 3615/4885PTGS1 3585/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.