Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.61 |
| ▸ | GCGR | P47871 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3344995 | 0.86 | TUBB4A (0.53) | MAPK14GCGRMEN1KMT2ACYP1A2 | |
| SCHEMBL5774019 | 0.85 | MAPT (0.54) | MAPK14GCGRMEN1KMT2ACYP1A2 | |
| SCHEMBL12971261 | 0.83 | ALDH1A1 (0.50) | MAPK14GCGRMEN1KMT2ACYP1A2 | |
| SCHEMBL1567586 | 0.81 | PTGER2 (0.53) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL18529243 | 0.80 | ALDH1A1 (0.43) | MAPK14GCGRMEN1KMT2ANPC1 | |
| SCHEMBL1156279 | 0.79 | KMT2A (0.67) | MAPK14GCGRMEN1KMT2ACYP1A2 | |
| SCHEMBL9015200 | 0.78 | SLC6A2 (0.49) | MAPK14GCGRCYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL16828410 | 0.77 | PRKCZ (0.51) | MAPK14GCGRMEN1KMT2APRKCZ | |
| SCHEMBL18342044 | 0.77 | MEN1 (0.55) | MAPK14GCGRMEN1KMT2ACYP1A2 | |
| SCHEMBL18529232 | 0.76 | HDAC3 (0.47) | MEN1KMT2ANPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4937255-A | Disubstituted pyrroles | BAYER AKTIENGESELLSCHAFT (DE) | 1990-06-26 | — | — | US | disclosed |
| EP-0334147-A1 | Disubstituted pyrroles | BAYER AG (DE) | 1989-09-27 | — | — | EP | disclosed |