Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535470 | 0.89 | SMN1; SMN2 (0.35) | SMN1; SMN2TSHRTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL9538333 | 0.83 | TP53 (0.36) | SMN1; SMN2TSHRTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL9536816 | 0.83 | SMN1; SMN2 (0.35) | SMN1; SMN2TSHRTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL10400976 | 0.82 | SMN1; SMN2 (0.37) | SMN1; SMN2TSHRTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL10400132 | 0.80 | MAPT (0.41) | ALDH1A1LMNACYP2C9HSD17B10HPGD | |
| SCHEMBL9504996 | 0.78 | CYP1A2 (0.37) | SMN1; SMN2TDP1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL10400134 | 0.78 | NPY1R (0.36) | TDP1L3MBTL1ALDH1A1LMNAKMT2A | |
| SCHEMBL10400912 | 0.78 | NPY1R (0.35) | SMN1; SMN2TSHRTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL9539862 | 0.75 | ALDH1A1 (0.35) | SMN1; SMN2TSHRALDH1A1LMNAMEN1 | |
| SCHEMBL10517233 | 0.74 | MAPK14 (0.36) | ALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4973690-A | PYRIMIDIN-2-YL UREAS, HERBICICES, PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1990-11-27 | — | — | US | disclosed |
| EP-0337944-A1 | Ureas | CIBA-GEIGY AG (CH) | 1989-10-18 | — | — | EP | disclosed |