Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10401161 | 0.89 | SMN1; SMN2 (0.37) | SMN1; SMN2TSHRLMNACRHBPCRHR2 | |
| SCHEMBL9504996 | 0.82 | CYP1A2 (0.37) | SMN1; SMN2LMNATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL9536816 | 0.81 | SMN1; SMN2 (0.35) | SMN1; SMN2TSHRLMNATDP1L3MBTL1 | |
| SCHEMBL9538333 | 0.81 | TP53 (0.36) | SMN1; SMN2TSHRLMNATDP1L3MBTL1 | |
| SCHEMBL10400976 | 0.80 | SMN1; SMN2 (0.37) | SMN1; SMN2TSHRLMNATDP1L3MBTL1 | |
| SCHEMBL10400132 | 0.77 | MAPT (0.41) | LMNAALDH1A1HPGDCYP1A2CYP2C19 | |
| SCHEMBL10400134 | 0.76 | NPY1R (0.36) | LMNATDP1L3MBTL1ALDH1A1CYP1A2 | |
| SCHEMBL10400912 | 0.76 | NPY1R (0.35) | SMN1; SMN2TSHRLMNATDP1L3MBTL1 | |
| SCHEMBL10400918 | 0.73 | ALDH1A1 (0.35) | SMN1; SMN2LMNAL3MBTL1ALDH1A1CYP1A2 | |
| SCHEMBL9539862 | 0.73 | ALDH1A1 (0.35) | SMN1; SMN2TSHRLMNAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337944-B1 | UREAS | CIBA-GEIGY AG (CH) | 1993-07-28 | — | — | EP | disclosed |
| US-4973690-A | PYRIMIDIN-2-YL UREAS, HERBICICES, PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1990-11-27 | — | — | US | disclosed |
| EP-0337944-A1 | Ureas | CIBA-GEIGY AG (CH) | 1989-10-18 | — | — | EP | disclosed |