Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 16/20 | 0.46 |
| ▸ | MMP3 | P08254 | 4/20 | 0.45 |
| ▸ | MMP2 | P08253 | 4/20 | 0.45 |
| ▸ | MMP9 | P14780 | 3/20 | 0.45 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 2/20 | 0.43 |
| ▸ | MMP7 | P09237 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9417215 | 0.85 | ITGB3 (0.49) | PTPN1 | |
| SCHEMBL9832615 | 0.85 | OPRM1 (0.40) | MMP1MMP3MMP2MMP9ADAM17 | |
| SCHEMBL9818534 | 0.85 | REN (0.45) | MMP1 | |
| SCHEMBL9833056 | 0.83 | REN (0.45) | MMP1MMP3MMP2MMP9ADAM17 | |
| SCHEMBL7374762 | 0.80 | MMP3 (0.43) | MMP1MMP3MMP2MMP9ADAM17 | |
| SCHEMBL1310175 | 0.80 | PTPN1 (0.56) | MMP3PTPN1 | |
| SCHEMBL1310180 | 0.80 | PTPN1 (0.56) | MMP3PTPN1 | |
| SCHEMBL11765581 | 0.79 | REN (0.54) | MMP1OPRM1PTPN1 | |
| SCHEMBL11759100 | 0.79 | REN (0.54) | MMP1OPRM1PTPN1 | |
| SCHEMBL9818552 | 0.79 | REN (0.45) | MMP1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4977277-A | INTERMEDIATES FOR RENIN INHIBITORS | ABBOTT LABORATORIES (US) | 1990-12-11 | — | — | US | disclosed |
| EP-0230266-A2 | Functionalized peptidyl aminodiols and -triols | ABBOTT LABORATORIES (US) | 1987-07-29 | — | — | EP | disclosed |