Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 3/20 | 0.45 |
| ▸ | PSMB8 | P28062 | 11/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 11/20 | 0.41 |
| ▸ | PSMB9 | P28065 | 3/20 | 0.40 |
| ▸ | PSMA1 | P25786 | 2/20 | 0.40 |
| ▸ | PSMB4 | P28070 | 2/20 | 0.40 |
| ▸ | PSMB10 | P40306 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 4/20 | 0.39 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.38 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.38 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.38 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.38 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.38 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.38 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.38 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.38 |
| ▸ | PSMB3 | P49720 | 1/20 | 0.38 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.38 |
| ▸ | PSMA6 | P60900 | 1/20 | 0.38 |
| ▸ | PSMA8 | Q8TAA3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7431573 | 0.89 | KMT2A (0.43) | — | |
| SCHEMBL10408619 | 0.85 | MMP1 (0.46) | MMP1 | |
| SCHEMBL9832615 | 0.80 | OPRM1 (0.40) | MMP1 | |
| SCHEMBL9417215 | 0.79 | ITGB3 (0.49) | — | |
| SCHEMBL9833056 | 0.77 | REN (0.45) | RENMMP1 | |
| SCHEMBL9417286 | 0.76 | QRFPR (0.46) | REN | |
| SCHEMBL7441871 | 0.76 | CTSS (0.53) | PSMB8PSMB5PSMB9PSMA1PSMB4 | |
| SCHEMBL9417266 | 0.76 | CTSS (0.53) | PSMB8PSMB5PSMB9PSMA1PSMB4 | |
| SCHEMBL7295919 | 0.75 | KMT2A (0.57) | — | |
| SCHEMBL7300089 | 0.75 | GAA (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5032577-A | Hypotensive | ABBOTT LABORATORIES (US) | 1991-07-16 | — | — | US | disclosed |