Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.38 |
| ▸ | ITGAV | P06756 | 11/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 6/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.37 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | ECE1 | P42892 | 1/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825638 | 0.77 | TGM2 (0.57) | ITGB3ITGAVITGA2B | |
| SCHEMBL4877584 | 0.77 | TGM2 (0.47) | ITGB3ITGAVITGA2B | |
| SCHEMBL9826660 | 0.73 | TGM2 (0.49) | ITGB3ITGAVITGA2B | |
| SCHEMBL9827314 | 0.72 | SLC7A5 (0.38) | ITGB3ITGA2B | |
| SCHEMBL9825943 | 0.72 | TGM2 (0.59) | ITGB3ITGAV | |
| SCHEMBL10795296 | 0.72 | TGM2 (0.44) | ITGB3ITGAVITGA2BMMEACE | |
| SCHEMBL9825261 | 0.70 | ITGB3 (0.34) | ITGB3ITGAVITGA2BMMEACE | |
| SCHEMBL9825407 | 0.69 | TGM2 (0.42) | ITGB3ITGA2B | |
| SCHEMBL9826397 | 0.69 | TGM2 (0.69) | — | |
| SCHEMBL9826404 | 0.68 | TGM2 (0.44) | ITGB3ITGAVITGA2BMMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4929630-A | SKIN DISORDERS, ACNE, 4,5-DIHYDROISOOXAZOLE PEPTIDES | SYNTEX (U.S.A.) INC. (US) | 1990-05-29 | — | — | US | disclosed |