Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL593010 | 1.00 | TSHR (0.53) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL9486435 | 1.00 | TSHR (0.53) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL1900543 | 1.00 | TSHR (0.53) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL5933161 | 1.00 | — | — | |
| SCHEMBL5606540 | 1.00 | TSHR (0.53) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL9486369 | 1.00 | TSHR (0.53) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL5932738 | 0.97 | — | — | |
| SCHEMBL1042256 | 0.80 | TSHR (0.53) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL2698662 | 0.80 | TSHR (0.53) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL7694903 | 0.76 | TSHR (0.57) | TSHRTHRBALDH1A1DNM1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030064954-A1 | Cationic amphiphilic 1,4-dihydropyridine derivatives useful for delivery of nucleotide containing compounds | SPONDULI SERVICES, LTD. (AU) | 2003-04-03 | — | — | US | claimed |
| EP-1261731-A1 | CATIONIC AMPHIPHILIC 1,4-DIHYDROPYRIDINE DERIVATIVES USEFUL FOR DELIVERY OF NUCLEOTIDE CONTAINING COMPOUNDS | Urtti, Arto (FI) | 2002-12-04 | — | — | EP | claimed |
| WO-2001062946-A1 | CATIONIC AMPHIPHILIC 1,4-DIHYDROPYRIDINE DERIVATIVES USEFUL FOR DELIVERY OF NUCLEOTIDE CONTAINING COMPOUNDS | URTTI ARTO (FI) | 2001-08-30 | — | — | WO | claimed |
| EP-0322209-B1 | COMPOUNDS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-02-10 | — | — | EP | claimed |
| US-4954339-A | ANTICHOLESTEROL AGENTS, SEQUESTERING | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1990-09-04 | — | — | US | claimed |
| WO-1989005828-A1 | COMPOUNDS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1989-06-29 | — | — | WO | claimed |
| EP-0322209-A1 | Compounds | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1989-06-28 | — | — | EP | claimed |
| US-20210298302-A1 | COMPOSITION INCLUDING AN ANTIMICROBIAL BOOSTING AGENT INCLUDING A SULTAINE AND METHODS OF INCREASING THE ANTIMICROBIAL EFFECTIVENESS OF A COMPOSITION | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2021-09-30 | — | — | US | disclosed |
| EP-2980180-A1 | PHOTOBASE GENERATOR | San-Apro Ltd. (JP) | 2016-02-03 | — | — | EP | disclosed |
| US-20160009737-A1 | PHOTOBASE GENERATOR | SAN-APRO LTD. (JP) | 2016-01-14 | — | — | US | disclosed |
| EP-2270114-B1 | PHOTOBASE GENERATOR | SAN APRO LTD (JP) | 2014-07-09 | — | — | EP | disclosed |
| US-8329771-B2 | Photobase generator | SAN-APRO LIMITED (JP) | 2012-12-11 | — | — | US | disclosed |
| US-7923522-B2 | excellent in stability of particle size and to be used for electronic materials; adding a hydrolyzable silane compound | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2011-04-12 | — | — | US | disclosed |
| EP-0373852-B1 | Compounds | SMITH KLINE FRENCH LAB (GB) | 1994-10-26 | — | — | EP | disclosed |
| EP-0322209-B1 | COMPOUNDS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-02-10 | — | — | EP | disclosed |
| US-4954339-A | ANTICHOLESTEROL AGENTS, SEQUESTERING | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1990-09-04 | — | — | US | disclosed |
| EP-0373852-A2 | Compounds | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1990-06-20 | — | — | EP | disclosed |
| WO-1989005828-A1 | COMPOUNDS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1989-06-29 | — | — | WO | disclosed |
| EP-0322209-A1 | Compounds | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1989-06-28 | — | — | EP | disclosed |
| US-4208401-A | STAIN INHIBITING | COLGATE-PALMOLIVE COMPANY (US) | 1980-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030064954-A1 | Cationic amphiphilic 1,4-dihydropyridine derivatives useful for delivery of nucleotide containing compounds | ACIN1, DNA2, KPNA1 | TSHR 4680/4885THRB 4695/4885ALDH1A1 2344/4885 |
| US-20210298302-A1 | COMPOSITION INCLUDING AN ANTIMICROBIAL BOOSTING AGENT INCLUDING A SULTAINE AND METHODS OF INCREASING THE ANTIMICROBIAL EFFECTIVENESS OF A COMPOSITION | SULT1A1, MGAM, IFNG | TSHR 2861/4885THRB 1113/4885ALDH1A1 1403/4885 |
| US-20160009737-A1 | PHOTOBASE GENERATOR | PSMC6, ARCN1, CRY1 | TSHR 2438/4885THRB 2456/4885ALDH1A1 1529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.