Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9853989 | 0.86 | LMNA (0.39) | KDM4EALDH1A1BLMALOX15MEN1 | |
| SCHEMBL10425283 | 0.81 | ALDH1A1 (0.52) | KDM4EALDH1A1 | |
| SCHEMBL9740818 | 0.81 | ALDH1A1 (0.52) | KDM4EALDH1A1 | |
| SCHEMBL170900 | 0.69 | KDM4E (0.56) | KDM4EALDH1A1BLMALOX15MEN1 | |
| SCHEMBL9250005 | 0.68 | ALDH1A1 (0.54) | KDM4EALDH1A1BLMALOX15NPSR1 | |
| SCHEMBL9250009 | 0.68 | ALDH1A1 (0.54) | KDM4EALDH1A1BLMALOX15NPSR1 | |
| SCHEMBL8507513 | 0.67 | MEN1 (0.41) | KDM4EALDH1A1BLMALOX15MEN1 | |
| SCHEMBL27314597 | 0.66 | ALDH1A1 (0.45) | KDM4EALDH1A1TDP1CYP3A4NPSR1 | |
| SCHEMBL9854029 | 0.66 | PTAFR (0.44) | KDM4EALDH1A1BLMALOX15 | |
| SCHEMBL9853999 | 0.66 | POLB (0.58) | KDM4EALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425134-A1 | Condensed pyrrolo derivatives, process for their preparation and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |