Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 8/20 | 0.36 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | BLVRB | P30043 | 1/20 | 0.34 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10429306 | 0.81 | XDH (0.42) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL10429327 | 0.68 | XDH (0.47) | XDHS1PR1 | |
| SCHEMBL10429332 | 0.67 | XDH (0.50) | XDH | |
| SCHEMBL10429330 | 0.63 | XDH (0.38) | XDH | |
| SCHEMBL17708376 | 0.62 | ALDH1A1 (0.49) | — | |
| SCHEMBL7165222 | 0.61 | F11 (0.40) | XDHPDE4AS1PR1 | |
| SCHEMBL19836420 | 0.61 | ACHE (0.46) | XDH | |
| SCHEMBL17708086 | 0.60 | VDR (0.49) | — | |
| SCHEMBL11454087 | 0.59 | HTR1A (0.63) | — | |
| SCHEMBL19836422 | 0.58 | SLC6A2 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4920119-A | XANTHINE OXIDASE INHIBITORS; CONTROL OR PREVENTION OF GOUT OR ISCHEMIA | HOFFMANN-LA ROCHE INC. (US) | 1990-04-24 | — | — | US | claimed |