Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 4/20 | 0.57 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 3/20 | 0.32 |
| ▸ | RXRG | P48443 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
| ▸ | HTR1B | P28222 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6533914 | 0.75 | THRB (0.41) | RXRAHDAC3HDAC6ALDH1A1HPGD | |
| SCHEMBL2343338 | 0.73 | GABRA1 (0.44) | RXRAGABRA1GABRB2HDAC3HDAC6 | |
| SCHEMBL21496239 | 0.71 | ALDH1A1 (0.47) | RXRAGABRA1GABRB2HDAC3HDAC6 | |
| SCHEMBL3952759 | 0.67 | MAPT (0.52) | ALDH1A1HPGDRAB9A | |
| SCHEMBL88554 | 0.67 | RXRA (0.50) | RXRAGABRA1GABRB2RXRBRXRG | |
| SCHEMBL11422095 | 0.67 | ALDH1A1 (0.50) | ALDH1A1CYP2C19TSHRRAB9A | |
| SCHEMBL13618776 | 0.66 | GABRA1 (0.52) | RXRAGABRA1GABRB2HDAC3HDAC6 | |
| SCHEMBL1336759 | 0.65 | GABRA1 (0.50) | RXRAGABRA1GABRB2HDAC3HDAC6 | |
| SCHEMBL29015814 | 0.64 | MEN1 (0.54) | GABRA1GABRB2ALDH1A1TRPV1HPGD | |
| SCHEMBL93161 | 0.64 | GABRA1 (0.69) | RXRAGABRA1GABRB2RXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0374824-A2 | Dental compositions containing bifunctional acrylic or methacrylic acid esters | THERA Patent GmbH & Co. KG Gesellschaft für industrielle Schutzrechte (DE) | 1990-06-27 | — | — | EP | disclosed |